Tampere University of Technology

TUTCRIS Research Portal

Research group: Molecular Signaling Lab

Research unit: Research Group

Organisation profile

 

The Molecular Signaling Lab (MS Lab) lead by Adjunct professor/Research fellow Meenakshisundaram Kandhavelu focuses on understanding molecular signaling network communication. These networks play crucial roles in gene expression regulation and cell fate determination. By investigating molecular signaling pathways that contribute to cancer and other diseases, research in MS Lab is breaking new ground. Improper intra and/or extracellular signal transduction affects cells well-being and lead to various diseases. Specifically, we study the canonical and non-canonical signaling pathways activated by GPCRs at single cell level. For this, our group deploys interdisciplinary research knowledge such as cell and molecular experimental approach, single cell imaging, image processing, signal processing, computational models and bioinformatics

 

Latest research outputs

  1. Published

    In vitro characterization of alkylaminophenols-induced cell death

    Doan, P., Anufrieva, O., Yli-Harja, O. & Kandhavelu, M. Feb 2018 In : European Journal of Pharmacology. 820, p. 229-234 6 p.

    Research output: Contribution to journalArticle

  2. Published

    Identification of novel GPR17-agonists by structural bioinformatics and signaling activation

    Saravanan, K. M., Palanivel, S., Yli-Harja, O. & Kandhavelu, M. 2018 In : International Journal of Biological Macromolecules. 106, p. 901-907

    Research output: Contribution to journalArticle

  3. Published

    Quantification of Transcriptional Noise at Single Cell Single Molecule Level

    Anufrieva, O., Yli-Harja, O. & Kandhavelu, M. Dec 2017 In : EC Microbiology. 13, 2, p. 45-54

    Research output: Contribution to journalArticle

Publications per year

No data available

ID: 10548573