Tampere University of Technology

TUTCRIS Research Portal

Research group: Molecular Signaling Lab

Research unit: Research Group

Organisation profile

 

The Molecular Signaling Lab (MS Lab) lead by Adjunct professor/Research fellow Meenakshisundaram Kandhavelu focuses on understanding molecular signaling network communication. These networks play crucial roles in gene expression regulation and cell fate determination. By investigating molecular signaling pathways that contribute to cancer and other diseases, research in MS Lab is breaking new ground. Improper intra and/or extracellular signal transduction affects cells well-being and lead to various diseases. Specifically, we study the canonical and non-canonical signaling pathways activated by GPCRs at single cell level. For this, our group deploys interdisciplinary research knowledge such as cell and molecular experimental approach, single cell imaging, image processing, signal processing, computational models and bioinformatics

 

Latest research outputs

  1. Published

    Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line

    Palanivel, S., Murugesan, A., Yli-Harja, O. & Kandhavelu, M., 1 Apr 2020, In : Saudi Pharmaceutical Journal. 28, 4, p. 495-503 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Published

    Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways

    Doan, P., Musa, A., Murugesan, A., Sipilä, V., Candeias, N. R., Emmert-Streib, F., Ruusuvuori, P., Granberg, K., Yli-Harja, O. & Kandhavelu, M., 10 Mar 2020, In : Cells. 9, 3, 21 p., 681.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Published

    Alkylamino Phenol Derivative Induces Apoptosis by Inhibiting EGFR Signaling Pathway in Breast Cancer Cells

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2020, In : Anti-Cancer Agents in Medicinal Chemistry. 20, 7, p. 809 - 819 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

Publications per year

No data available

ID: 10548573