Tampere University of Technology

TUTCRIS Research Portal

Research group: Molecular Signaling Lab

Research unit: Research Group

  1. Published

    2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma

    Viswanathan, A., Kute, D., Musa, A., Mani, S. K., Sipilä, V., Emmert-Streib, F., Zubkov, F. I., Gurbanov, A. V., Yli-Harja, O. & Kandhavelu, M., 15 Mar 2019, In : European Journal of Medicinal Chemistry. 166, p. 291 - 303

    Research output: Contribution to journalArticleScientificpeer-review

  2. Published

    Alkylaminophenol induces G1/S phase cell cycle arrest in glioblastoma cells through p53 and cyclin-dependent kinase signaling pathway

    Doan, P., Musa, A., Candeias, N. R., Emmert-Streib, F., Yli-Harja, O. & Kandhavelu, M., 2019, In : FRONTIERS IN PHARMACOLOGY. 10, APR, 330.

    Research output: Contribution to journalArticleScientificpeer-review

  3. Published

    Analysis of Ca2+ and cAMP signaling regulated by GPR17 at single cell level.

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 5 Dec 2014, p. 88. 1 p.

    Research output: Other conference contributionPaper, poster or abstractScientific

  4. Published

    Antibacterial and antitumor properties of alkylaminophenols derived from Petasis borono-Mannich multicomponent reaction

    Rafael Candeias, N., Rijo, P. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  5. Published

    Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line

    Palanivel, S., Murugesan, A., Yli-Harja, O. & Kandhavelu, M., 1 Apr 2020, In : Saudi Pharmaceutical Journal. 28, 4, p. 495-503 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  6. Published

    Antimicrobial activity and molecular analysis of azoderivatives of β-diketones

    Viswanathan, A., Sala, A., Yli-Harja, O. & Kandhavelu, M., 23 Jan 2015, In : European Journal of Pharmaceutical Sciences. 66, p. 83-89 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  7. Published

    Base catalysed N-functionalisation of boroxazolidones

    J., R., Mannoja, J., Nguyen, T., N., A., N. M., K., Franzén, R. G., Kandhavelu, M. & Candeias, N. R., 2017, In : RSC Advances. 7, 33, p. 20620-20627 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  8. Published

    Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)

    Viswanathan, A., Musa, A., Murugesan, A., Vale, J. R., Afonso, C. A. M., Konda Mani, S., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 12 Dec 2019, In : Cells. 8, 12, 18 p., 1624.

    Research output: Contribution to journalArticleScientificpeer-review

  9. Published

    Development of efficient cell segmentation tool for microscope image

    Sandberg, O., Palanivel, S., Doan, P., Yli-Harja, O. & Kandhavelu, M., 2015.

    Research output: Other conference contributionPaper, poster or abstractScientific

  10. Published

    Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways

    Doan, P., Musa, A., Murugesan, A., Sipilä, V., Candeias, N. R., Emmert-Streib, F., Ruusuvuori, P., Granberg, K., Yli-Harja, O. & Kandhavelu, M., 10 Mar 2020, In : Cells. 9, 3, 21 p., 681.

    Research output: Contribution to journalArticleScientificpeer-review

  11. Published

    GPR17 is a novel target for personalized medicine for glioblastoma

    Doan, P., Musa, A., Nguyen, T., Saravanan, K. M., Sipilä, V., Emmert-Streib, F., Yli-Harja, O. & Kandhavelu, M., 2018, The 4th Annual Finnish Symposium on Brain Tumors, FIBTRA: Vanajanlinna, Hämeenlinna, 29-30 November 2018.

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

  12. Published

    hGPR17 signaling cascade effects mitochondrial function

    Kandhavelu, M., 2016, In : The FEBS Journal. 283, S1

    Research output: Contribution to journalMeeting AbstractScientificpeer-review

  13. Published

    Identification of novel GPR17-agonists by structural bioinformatics and signaling activation

    Saravanan, KM., Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2018, In : International Journal of Biological Macromolecules. 106, p. 901-907

    Research output: Contribution to journalArticleScientificpeer-review

  14. Published

    Image-based cell cycle analysis at single cell level

    Sipilä, V., Doan, P., Ruusuvuori, P., Yli-Harja, O. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  15. Published

    Induction of cell cycle arrest and apoptosis of glioma cancer stem cells

    Doan, P., Sipilä, V., Yli-Harja, O., Rafael Candeias, N. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  16. Published

    Investigation of novel long-chain diol derivatives as potential growth inhibitors of glioblastoma

    Zhurina, A., Viswanathan, A., Assoah, B., Paakkunainen, A., Yli-Harja, O., Rafael Candeias, N. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  17. Published

    Investigation of small molecule effects in human embryonic kidney cell lines

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2015, p. 53.

    Research output: Other conference contributionPaper, poster or abstractScientific

  18. Published

    In vitro anti-glioblastoma activity of L-valine derived boroxazolidones

    Viswanathan, A., Sebastianelli, G., Brown, K., Raunio, J., Sipilä, V., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 5 Jul 2019, In : European Journal of Pharmacology. 854, p. 194-200 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  19. Published

    In vitro characterization of alkylaminophenols-induced cell death

    Doan, P., Anufrieva, O., Yli-Harja, O. & Kandhavelu, M., Feb 2018, In : European Journal of Pharmacology. 820, p. 229-234 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  20. Published

    Novel small molecules are found to exhibit cytotoxic effect on osteosarcoma cells

    Karjalainen, A., Doan, P., Sandberg, O., Yli-Harja, O., Rafael Candeias, N. & Kandhavelu, M., 2015, p. 22.

    Research output: Other conference contributionPaper, poster or abstractScientific

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