Tampere University of Technology

TUTCRIS Research Portal

Research group: Molecular Signaling Lab

Research unit: Research Group

  1. Published

    Transcription closed and open complex dynamics studies reveal balance between genetic determinants and co-factors

    Sala, A., Shoaib, M., Anufrieva, O., Mutharasu, G., Hoque, R. J., Yli-Harja, O. & Kandhavelu, M., 2015, In : Physical Biology. 12, 3, 036003.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Published

    Synthesis of phenol-derivatives and biological screening for anticancer activity

    Karjalainen, A., Doan, P., Sandberg, O., Chandraseelan, J. G., Yli-Harja, O., R. Candeias, N. & Kandhavelu, M., 2017, In : Anti-Cancer Agents in Medicinal Chemistry. 17, 12, p. 1710-1720

    Research output: Contribution to journalArticleScientificpeer-review

  3. Published

    Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent

    Le, H. T. T., Rimpilainen, T., Konda Mani, S., Murugesan, A., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 12 Dec 2019, In : Scientific Reports. 9, 18938.

    Research output: Contribution to journalArticleScientificpeer-review

  4. Published

    Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines

    Doan, P., Karjalainen, A., Chandraseelan, J. G., Sandberg, O., Yli-Harja, O., Rosholm, T., Franzén, R., R. Candeias, N. & Kandhavelu, M., May 2016, In : European Journal of Medicinal Chemistry. 120, p. 296-303

    Research output: Contribution to journalArticleScientificpeer-review

  5. Published

    Study of the kinetics of transcription as a function of the cell growth phase

    Sala, A., Sanches Ribeiro, A. & Kandhavelu, M., 1 Jul 2013, FEBS journal. p. 570-570

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

  6. Published

    Regulation mitochondrial dysfunction function by human GPR17

    Kandhavelu, M., 2016.

    Research output: Other conference contributionPaper, poster or abstractScientific

  7. Published

    Real-time observation of bacterial gene expression noise

    Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., Jun 2016, In : Nano Communication Networks. 8, p. 68-75

    Research output: Contribution to journalArticleScientificpeer-review

  8. Published

    Quantification of Transcriptional Noise at Single Cell Single Molecule Level

    Anufrieva, O., Yli-Harja, O. & Kandhavelu, M., Dec 2017, In : EC Microbiology. 13, 2, p. 45-54

    Research output: Contribution to journalArticleProfessional

  9. Published

    QSAR and Molecular Docking Analysis of synthetic compounds against Breast Cancer Targets

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  10. Published

    Protein-protein interaction and coarse grained simulation study of Glioblastoma Multiforme reveals novel pathways of GPR17

    Mutharasu, G., Yli-harja, O. & Kandhavelu, M., 2014, In : TASK Quarterly. 18, 4, p. 321-325 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  11. Published

    Phase-dependent dynamics of the lac promoter under nutrient stress

    Viswanathan, A., Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., 19 Apr 2016, In : Research in Microbiology. 167, 6, p. 451-461

    Research output: Contribution to journalArticleScientificpeer-review

  12. Published

    Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences

    Sala, A., Shoaib, M., Anufrieva, O., Mutharasu, G., Yli-Harja, O. & Kandhavelu, M., 2015, In : mBio. 6, 1, 9 p., e02182-14.

    Research output: Contribution to journalArticleScientificpeer-review

  13. Published

    Novel small molecules are found to exhibit cytotoxic effect on osteosarcoma cells

    Karjalainen, A., Doan, P., Sandberg, O., Yli-Harja, O., Rafael Candeias, N. & Kandhavelu, M., 2015, p. 22.

    Research output: Other conference contributionPaper, poster or abstractScientific

  14. Published

    In vitro characterization of alkylaminophenols-induced cell death

    Doan, P., Anufrieva, O., Yli-Harja, O. & Kandhavelu, M., Feb 2018, In : European Journal of Pharmacology. 820, p. 229-234 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  15. Published

    In vitro anti-glioblastoma activity of L-valine derived boroxazolidones

    Viswanathan, A., Sebastianelli, G., Brown, K., Raunio, J., Sipilä, V., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 5 Jul 2019, In : European Journal of Pharmacology. 854, p. 194-200 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  16. Published

    Investigation of small molecule effects in human embryonic kidney cell lines

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2015, p. 53.

    Research output: Other conference contributionPaper, poster or abstractScientific

  17. Published

    Investigation of novel long-chain diol derivatives as potential growth inhibitors of glioblastoma

    Zhurina, A., Viswanathan, A., Assoah, B., Paakkunainen, A., Yli-Harja, O., Rafael Candeias, N. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  18. Published

    Induction of cell cycle arrest and apoptosis of glioma cancer stem cells

    Doan, P., Sipilä, V., Yli-Harja, O., Rafael Candeias, N. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  19. Published

    Image-based cell cycle analysis at single cell level

    Sipilä, V., Doan, P., Ruusuvuori, P., Yli-Harja, O. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  20. Published

    Identification of novel GPR17-agonists by structural bioinformatics and signaling activation

    Saravanan, KM., Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2018, In : International Journal of Biological Macromolecules. 106, p. 901-907

    Research output: Contribution to journalArticleScientificpeer-review

  21. Published

    hGPR17 signaling cascade effects mitochondrial function

    Kandhavelu, M., 2016, In : The FEBS Journal. 283, S1

    Research output: Contribution to journalMeeting AbstractScientificpeer-review

  22. Published

    GPR17 is a novel target for personalized medicine for glioblastoma

    Doan, P., Musa, A., Nguyen, T., Saravanan, K. M., Sipilä, V., Emmert-Streib, F., Yli-Harja, O. & Kandhavelu, M., 2018, The 4th Annual Finnish Symposium on Brain Tumors, FIBTRA: Vanajanlinna, Hämeenlinna, 29-30 November 2018.

    Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

  23. Published

    Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways

    Doan, P., Musa, A., Murugesan, A., Sipilä, V., Candeias, N. R., Emmert-Streib, F., Ruusuvuori, P., Granberg, K., Yli-Harja, O. & Kandhavelu, M., 10 Mar 2020, In : Cells. 9, 3, 21 p., 681.

    Research output: Contribution to journalArticleScientificpeer-review

  24. Published

    Development of efficient cell segmentation tool for microscope image

    Sandberg, O., Palanivel, S., Doan, P., Yli-Harja, O. & Kandhavelu, M., 2015.

    Research output: Other conference contributionPaper, poster or abstractScientific

  25. Published

    Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)

    Viswanathan, A., Musa, A., Murugesan, A., Vale, J. R., Afonso, C. A. M., Konda Mani, S., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 12 Dec 2019, In : Cells. 8, 12, 18 p., 1624.

    Research output: Contribution to journalArticleScientificpeer-review

  26. Published

    Base catalysed N-functionalisation of boroxazolidones

    J., R., Mannoja, J., Nguyen, T., N., A., N. M., K., Franzén, R. G., Kandhavelu, M. & Candeias, N. R., 2017, In : RSC Advances. 7, 33, p. 20620-20627 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  27. Published

    Antimicrobial activity and molecular analysis of azoderivatives of β-diketones

    Viswanathan, A., Sala, A., Yli-Harja, O. & Kandhavelu, M., 23 Jan 2015, In : European Journal of Pharmaceutical Sciences. 66, p. 83-89 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  28. Published

    Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line

    Palanivel, S., Murugesan, A., Yli-Harja, O. & Kandhavelu, M., 1 Apr 2020, In : Saudi Pharmaceutical Journal. 28, 4, p. 495-503 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  29. Published

    Antibacterial and antitumor properties of alkylaminophenols derived from Petasis borono-Mannich multicomponent reaction

    Rafael Candeias, N., Rijo, P. & Kandhavelu, M., 2017.

    Research output: Other conference contributionPaper, poster or abstractScientific

  30. Published

    Analysis of Ca2+ and cAMP signaling regulated by GPR17 at single cell level.

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 5 Dec 2014, p. 88. 1 p.

    Research output: Other conference contributionPaper, poster or abstractScientific

  31. Published

    Alkylaminophenol induces G1/S phase cell cycle arrest in glioblastoma cells through p53 and cyclin-dependent kinase signaling pathway

    Doan, P., Musa, A., Candeias, N. R., Emmert-Streib, F., Yli-Harja, O. & Kandhavelu, M., 2019, In : FRONTIERS IN PHARMACOLOGY. 10, APR, 330.

    Research output: Contribution to journalArticleScientificpeer-review

  32. Published

    2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma

    Viswanathan, A., Kute, D., Musa, A., Mani, S. K., Sipilä, V., Emmert-Streib, F., Zubkov, F. I., Gurbanov, A. V., Yli-Harja, O. & Kandhavelu, M., 15 Mar 2019, In : European Journal of Medicinal Chemistry. 166, p. 291 - 303

    Research output: Contribution to journalArticleScientificpeer-review

ID: 10548573