Tampere University of Technology

TUTCRIS Research Portal

Research group: Molecular Signaling Lab

Research unit: Research Group

  1. Article › Scientific › Peer-reviewed
  2. Published

    2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma

    Viswanathan, A., Kute, D., Musa, A., Mani, S. K., Sipilä, V., Emmert-Streib, F., Zubkov, F. I., Gurbanov, A. V., Yli-Harja, O. & Kandhavelu, M., 15 Mar 2019, In : European Journal of Medicinal Chemistry. 166, p. 291 - 303

    Research output: Contribution to journalArticleScientificpeer-review

  3. Published

    Alkylamino Phenol Derivative Induces Apoptosis by Inhibiting EGFR Signaling Pathway in Breast Cancer Cells

    Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2020, In : Anti-Cancer Agents in Medicinal Chemistry. 20, 7, p. 809 - 819 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

  4. Published

    Alkylaminophenol induces G1/S phase cell cycle arrest in glioblastoma cells through p53 and cyclin-dependent kinase signaling pathway

    Doan, P., Musa, A., Candeias, N. R., Emmert-Streib, F., Yli-Harja, O. & Kandhavelu, M., 2019, In : FRONTIERS IN PHARMACOLOGY. 10, APR, 330.

    Research output: Contribution to journalArticleScientificpeer-review

  5. Published

    Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line

    Palanivel, S., Murugesan, A., Yli-Harja, O. & Kandhavelu, M., 1 Apr 2020, In : Saudi Pharmaceutical Journal. 28, 4, p. 495-503 9 p.

    Research output: Contribution to journalArticleScientificpeer-review

  6. Published

    Antimicrobial activity and molecular analysis of azoderivatives of β-diketones

    Viswanathan, A., Sala, A., Yli-Harja, O. & Kandhavelu, M., 23 Jan 2015, In : European Journal of Pharmaceutical Sciences. 66, p. 83-89 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  7. Published

    Base catalysed N-functionalisation of boroxazolidones

    J., R., Mannoja, J., Nguyen, T., N., A., N. M., K., Franzén, R. G., Kandhavelu, M. & Candeias, N. R., 2017, In : RSC Advances. 7, 33, p. 20620-20627 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  8. Published

    Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)

    Viswanathan, A., Musa, A., Murugesan, A., Vale, J. R., Afonso, C. A. M., Konda Mani, S., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 12 Dec 2019, In : Cells. 8, 12, 18 p., 1624.

    Research output: Contribution to journalArticleScientificpeer-review

  9. Published

    Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways

    Doan, P., Musa, A., Murugesan, A., Sipilä, V., Candeias, N. R., Emmert-Streib, F., Ruusuvuori, P., Granberg, K., Yli-Harja, O. & Kandhavelu, M., 10 Mar 2020, In : Cells. 9, 3, 21 p., 681.

    Research output: Contribution to journalArticleScientificpeer-review

  10. Published

    Identification of novel GPR17-agonists by structural bioinformatics and signaling activation

    Saravanan, KM., Palanivel, S., Yli-Harja, O. & Kandhavelu, M., 2018, In : International Journal of Biological Macromolecules. 106, p. 901-907

    Research output: Contribution to journalArticleScientificpeer-review

  11. Published

    In vitro anti-glioblastoma activity of L-valine derived boroxazolidones

    Viswanathan, A., Sebastianelli, G., Brown, K., Raunio, J., Sipilä, V., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 5 Jul 2019, In : European Journal of Pharmacology. 854, p. 194-200 7 p.

    Research output: Contribution to journalArticleScientificpeer-review

  12. Published

    In vitro characterization of alkylaminophenols-induced cell death

    Doan, P., Anufrieva, O., Yli-Harja, O. & Kandhavelu, M., Feb 2018, In : European Journal of Pharmacology. 820, p. 229-234 6 p.

    Research output: Contribution to journalArticleScientificpeer-review

  13. Published

    Origins of Transcriptional Transition: Balance between Upstream and Downstream Regulatory Gene Sequences

    Sala, A., Shoaib, M., Anufrieva, O., Mutharasu, G., Yli-Harja, O. & Kandhavelu, M., 2015, In : mBio. 6, 1, 9 p., e02182-14.

    Research output: Contribution to journalArticleScientificpeer-review

  14. Published

    Phase-dependent dynamics of the lac promoter under nutrient stress

    Viswanathan, A., Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., 19 Apr 2016, In : Research in Microbiology. 167, 6, p. 451-461

    Research output: Contribution to journalArticleScientificpeer-review

  15. Published

    Protein-protein interaction and coarse grained simulation study of Glioblastoma Multiforme reveals novel pathways of GPR17

    Mutharasu, G., Yli-harja, O. & Kandhavelu, M., 2014, In : TASK Quarterly. 18, 4, p. 321-325 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  16. Published

    Real-time observation of bacterial gene expression noise

    Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., Jun 2016, In : Nano Communication Networks. 8, p. 68-75

    Research output: Contribution to journalArticleScientificpeer-review

  17. Published

    Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines

    Doan, P., Karjalainen, A., Chandraseelan, J. G., Sandberg, O., Yli-Harja, O., Rosholm, T., Franzén, R., R. Candeias, N. & Kandhavelu, M., May 2016, In : European Journal of Medicinal Chemistry. 120, p. 296-303

    Research output: Contribution to journalArticleScientificpeer-review

  18. Published

    Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent

    Le, H. T. T., Rimpilainen, T., Konda Mani, S., Murugesan, A., Yli-Harja, O., Candeias, N. R. & Kandhavelu, M., 12 Dec 2019, In : Scientific Reports. 9, 18938.

    Research output: Contribution to journalArticleScientificpeer-review

  19. Published

    Synthesis of phenol-derivatives and biological screening for anticancer activity

    Karjalainen, A., Doan, P., Sandberg, O., Chandraseelan, J. G., Yli-Harja, O., R. Candeias, N. & Kandhavelu, M., 2017, In : Anti-Cancer Agents in Medicinal Chemistry. 17, 12, p. 1710-1720

    Research output: Contribution to journalArticleScientificpeer-review

  20. Published

    Transcription closed and open complex dynamics studies reveal balance between genetic determinants and co-factors

    Sala, A., Shoaib, M., Anufrieva, O., Mutharasu, G., Hoque, R. J., Yli-Harja, O. & Kandhavelu, M., 2015, In : Physical Biology. 12, 3, 036003.

    Research output: Contribution to journalArticleScientificpeer-review

  21. Article › Professional
  22. Published

    Quantification of Transcriptional Noise at Single Cell Single Molecule Level

    Anufrieva, O., Yli-Harja, O. & Kandhavelu, M., Dec 2017, In : EC Microbiology. 13, 2, p. 45-54

    Research output: Contribution to journalArticleProfessional

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