Tampere University of Technology

TUTCRIS Research Portal

Research group: Molecular Signaling Lab

Research unit: Research Group

Organisation profile

Molecular signaling network plays the crucial role in gene expression regulation and cell fate determination. We investigate the molecular signaling pathways of cancer and other diseases. Improper intra and/or extracellular signal transduction affects cells well-being and lead to various diseases. Specifically, we study the canonical and non-canonical signaling pathways activated by membrane receptor at single cell level. For this, our group deploys interdisciplinary research knowledge such as Biosensor and biomeasurements, Pharmaceutical sciences, Single cell imaging, Molecular signal processing, Computational models and bioinformatics. The group develops and apply synthetic signaling compounds, biosensor, modeling, and simulation health and disease. We are the part of Computational Systems Biology Group, The Faculty of Biomedical Sciences and Engineering at BioMediTech–Tampere University of Technology.

Latest research outputs

  1. Published

    Base catalysed N-functionalisation of boroxazolidones

    J., R., Mannoja, J., Nguyen, T., N., A., N. M., K., Franzén, R. G., Kandhavelu, M. & Candeias, N. R., 2017, In : RSC Advances. 7, 33, p. 20620-20627 8 p.

    Research output: Contribution to journalArticleScientificpeer-review

  2. Published

    Synthesis of phenol-derivatives and biological screening for anticancer activity

    Karjalainen, A., Doan, P., Sandberg, O., Chandraseelan, J. G., Yli-Harja, O., R. Candeias, N. & Kandhavelu, M., 2017, In : Anti-Cancer Agents in Medicinal Chemistry. 17, 12, p. 1710-1720

    Research output: Contribution to journalArticleScientificpeer-review

  3. Published

    Real-time observation of bacterial gene expression noise

    Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., Jun 2016, In : Nano Communication Networks. 8, p. 68-75

    Research output: Contribution to journalArticleScientificpeer-review

Publications per year

No data available

ID: 24527