Research group: Molecular Signaling Lab
Research unit: Research Group
Organisation profile
Molecular signaling network plays the crucial role in gene expression regulation and cell fate determination. We investigate the molecular signaling pathways of cancer and other diseases. Improper intra and/or extracellular signal transduction affects cells well-being and lead to various diseases. Specifically, we study the canonical and non-canonical signaling pathways activated by membrane receptor at single cell level. For this, our group deploys interdisciplinary research knowledge such as Biosensor and biomeasurements, Pharmaceutical sciences, Single cell imaging, Molecular signal processing, Computational models and bioinformatics. The group develops and apply synthetic signaling compounds, biosensor, modeling, and simulation health and disease. We are the part of Computational Systems Biology Group, The Faculty of Biomedical Sciences and Engineering at BioMediTech–Tampere University of Technology.
Latest research outputs
- Published
Base catalysed N-functionalisation of boroxazolidones
J., R., Mannoja, J., Nguyen, T., N., A., N. M., K., Franzén, R. G., Kandhavelu, M. & Candeias, N. R., 2017, In : RSC Advances. 7, 33, p. 20620-20627 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Full text:
- Published
Synthesis of phenol-derivatives and biological screening for anticancer activity
Karjalainen, A., Doan, P., Sandberg, O., Chandraseelan, J. G., Yli-Harja, O., R. Candeias, N. & Kandhavelu, M., 2017, In : Anti-Cancer Agents in Medicinal Chemistry. 17, 12, p. 1710-1720Research output: Contribution to journal › Article › Scientific › peer-review
Full text:
- Published
Real-time observation of bacterial gene expression noise
Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., Jun 2016, In : Nano Communication Networks. 8, p. 68-75Research output: Contribution to journal › Article › Scientific › peer-review
Full text:
Publications per year
ID: 24527