Tampere University of Technology

TUTCRIS Research Portal

Benchmarking of algorithms for 3D tissue reconstruction

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review


Original languageEnglish
Title of host publication2016 IEEE International Conference on Image Processing (ICIP)
Number of pages5
ISBN (Electronic)978-1-4673-9961-6
Publication statusPublished - 19 Aug 2016
Publication typeA4 Article in a conference publication
EventIEEE International Conference on Image Processing -
Duration: 1 Jan 1900 → …

Publication series

ISSN (Electronic)2381-8549


ConferenceIEEE International Conference on Image Processing
Period1/01/00 → …


Studying tissue structure in 3D is beneficial in many applications. Reconstructing the structure based on histological sections has the advantages of high resolution and compatibility with conventional staining and interpretation techniques. However, obtaining an accurate 3D reconstruction based on a sequence of 2D sections is a difficult task. Evaluating the accuracy of such reconstructions is also challenging and it is often performed based only on visual inspections or a single indirect numerical measure. Here, we present a benchmarking framework composed of a panel of complementary metrics for assessing the quality of 3D reconstructions. We then apply the framework to evaluate the performance of several popular image registration algorithms in this context.


  • Benchmark testing, Image reconstruction, Image registration, Indexes, Measurement, Standards, Three-dimensional displays, 3D reconstruction, benchmark, digital pathology, histology

Publication forum classification

Field of science, Statistics Finland