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Childhood leukaemia risks: From unexplained findings near nuclear installations to recommendations for future research

Research output: Contribution to journalReview ArticleScientificpeer-review

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Childhood leukaemia risks : From unexplained findings near nuclear installations to recommendations for future research. / Laurier, D.; Grosche, B.; Auvinen, A.; Clavel, J.; Cobaleda, C.; Dehos, A.; Hornhardt, S.; Jacob, S.; Kaatsch, P.; Kosti, O.; Kuehni, C.; Lightfoot, T.; Spycher, B.; Van Nieuwenhuyse, A.; Wakeford, R.; Ziegelberger, G.

In: JOURNAL OF RADIOLOGICAL PROTECTION, Vol. 34, No. 3, 2014.

Research output: Contribution to journalReview ArticleScientificpeer-review

Harvard

Laurier, D, Grosche, B, Auvinen, A, Clavel, J, Cobaleda, C, Dehos, A, Hornhardt, S, Jacob, S, Kaatsch, P, Kosti, O, Kuehni, C, Lightfoot, T, Spycher, B, Van Nieuwenhuyse, A, Wakeford, R & Ziegelberger, G 2014, 'Childhood leukaemia risks: From unexplained findings near nuclear installations to recommendations for future research', JOURNAL OF RADIOLOGICAL PROTECTION, vol. 34, no. 3. https://doi.org/10.1088/0952-4746/34/3/R53

APA

Laurier, D., Grosche, B., Auvinen, A., Clavel, J., Cobaleda, C., Dehos, A., ... Ziegelberger, G. (2014). Childhood leukaemia risks: From unexplained findings near nuclear installations to recommendations for future research. JOURNAL OF RADIOLOGICAL PROTECTION, 34(3). https://doi.org/10.1088/0952-4746/34/3/R53

Vancouver

Laurier D, Grosche B, Auvinen A, Clavel J, Cobaleda C, Dehos A et al. Childhood leukaemia risks: From unexplained findings near nuclear installations to recommendations for future research. JOURNAL OF RADIOLOGICAL PROTECTION. 2014;34(3). https://doi.org/10.1088/0952-4746/34/3/R53

Author

Laurier, D. ; Grosche, B. ; Auvinen, A. ; Clavel, J. ; Cobaleda, C. ; Dehos, A. ; Hornhardt, S. ; Jacob, S. ; Kaatsch, P. ; Kosti, O. ; Kuehni, C. ; Lightfoot, T. ; Spycher, B. ; Van Nieuwenhuyse, A. ; Wakeford, R. ; Ziegelberger, G. / Childhood leukaemia risks : From unexplained findings near nuclear installations to recommendations for future research. In: JOURNAL OF RADIOLOGICAL PROTECTION. 2014 ; Vol. 34, No. 3.

Bibtex - Download

@article{5540660db63f4198a6e8cf2bd4623264,
title = "Childhood leukaemia risks: From unexplained findings near nuclear installations to recommendations for future research",
abstract = "Recent findings related to childhood leukaemia incidence near nuclear installations have raised questions which can be answered neither by current knowledge on radiation risk nor by other established risk factors. In 2012, a workshop was organised on this topic with two objectives: (a) review of results and discussion of methodological limitations of studies near nuclear installations; (b) identification of directions for future research into the causes and pathogenesis of childhood leukaemia. The workshop gathered 42 participants from different disciplines, extending widely outside of the radiation protection field. Regarding the proximity of nuclear installations, the need for continuous surveillance of childhood leukaemia incidence was highlighted, including a better characterisation of the local population. The creation of collaborative working groups was recommended for consistency in methodologies and the possibility of combining data for future analyses. Regarding the causes of childhood leukaemia, major fields of research were discussed (environmental risk factors, genetics, infections, immunity, stem cells, experimental research). The need for multidisciplinary collaboration in developing research activities was underlined, including the prevalence of potential predisposition markers and investigating further the infectious aetiology hypothesis. Animal studies and genetic/epigenetic approaches appear of great interest. Routes for future research were pointed out.",
keywords = "Aetiology, Childhood, Epidemiology, Leukaemia, Nuclear installations, Risk",
author = "D. Laurier and B. Grosche and A. Auvinen and J. Clavel and C. Cobaleda and A. Dehos and S. Hornhardt and S. Jacob and P. Kaatsch and O. Kosti and C. Kuehni and T. Lightfoot and B. Spycher and {Van Nieuwenhuyse}, A. and R. Wakeford and G. Ziegelberger",
year = "2014",
doi = "10.1088/0952-4746/34/3/R53",
language = "English",
volume = "34",
journal = "JOURNAL OF RADIOLOGICAL PROTECTION",
issn = "0952-4746",
publisher = "IOP Publishing",
number = "3",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Childhood leukaemia risks

T2 - From unexplained findings near nuclear installations to recommendations for future research

AU - Laurier, D.

AU - Grosche, B.

AU - Auvinen, A.

AU - Clavel, J.

AU - Cobaleda, C.

AU - Dehos, A.

AU - Hornhardt, S.

AU - Jacob, S.

AU - Kaatsch, P.

AU - Kosti, O.

AU - Kuehni, C.

AU - Lightfoot, T.

AU - Spycher, B.

AU - Van Nieuwenhuyse, A.

AU - Wakeford, R.

AU - Ziegelberger, G.

PY - 2014

Y1 - 2014

N2 - Recent findings related to childhood leukaemia incidence near nuclear installations have raised questions which can be answered neither by current knowledge on radiation risk nor by other established risk factors. In 2012, a workshop was organised on this topic with two objectives: (a) review of results and discussion of methodological limitations of studies near nuclear installations; (b) identification of directions for future research into the causes and pathogenesis of childhood leukaemia. The workshop gathered 42 participants from different disciplines, extending widely outside of the radiation protection field. Regarding the proximity of nuclear installations, the need for continuous surveillance of childhood leukaemia incidence was highlighted, including a better characterisation of the local population. The creation of collaborative working groups was recommended for consistency in methodologies and the possibility of combining data for future analyses. Regarding the causes of childhood leukaemia, major fields of research were discussed (environmental risk factors, genetics, infections, immunity, stem cells, experimental research). The need for multidisciplinary collaboration in developing research activities was underlined, including the prevalence of potential predisposition markers and investigating further the infectious aetiology hypothesis. Animal studies and genetic/epigenetic approaches appear of great interest. Routes for future research were pointed out.

AB - Recent findings related to childhood leukaemia incidence near nuclear installations have raised questions which can be answered neither by current knowledge on radiation risk nor by other established risk factors. In 2012, a workshop was organised on this topic with two objectives: (a) review of results and discussion of methodological limitations of studies near nuclear installations; (b) identification of directions for future research into the causes and pathogenesis of childhood leukaemia. The workshop gathered 42 participants from different disciplines, extending widely outside of the radiation protection field. Regarding the proximity of nuclear installations, the need for continuous surveillance of childhood leukaemia incidence was highlighted, including a better characterisation of the local population. The creation of collaborative working groups was recommended for consistency in methodologies and the possibility of combining data for future analyses. Regarding the causes of childhood leukaemia, major fields of research were discussed (environmental risk factors, genetics, infections, immunity, stem cells, experimental research). The need for multidisciplinary collaboration in developing research activities was underlined, including the prevalence of potential predisposition markers and investigating further the infectious aetiology hypothesis. Animal studies and genetic/epigenetic approaches appear of great interest. Routes for future research were pointed out.

KW - Aetiology

KW - Childhood

KW - Epidemiology

KW - Leukaemia

KW - Nuclear installations

KW - Risk

UR - http://www.scopus.com/inward/record.url?scp=84908574038&partnerID=8YFLogxK

U2 - 10.1088/0952-4746/34/3/R53

DO - 10.1088/0952-4746/34/3/R53

M3 - Review Article

VL - 34

JO - JOURNAL OF RADIOLOGICAL PROTECTION

JF - JOURNAL OF RADIOLOGICAL PROTECTION

SN - 0952-4746

IS - 3

ER -