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Common features of chromatin in aging and cancer: Cause or coincidence?

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Common features of chromatin in aging and cancer : Cause or coincidence? / Zane, Linda; Sharma, Vivek; Misteli, Tom.

In: TRENDS IN CELL BIOLOGY, Vol. 24, No. 11, 2014, p. 686-694.

Research output: Contribution to journalReview ArticleScientificpeer-review

Harvard

Zane, L, Sharma, V & Misteli, T 2014, 'Common features of chromatin in aging and cancer: Cause or coincidence?', TRENDS IN CELL BIOLOGY, vol. 24, no. 11, pp. 686-694. https://doi.org/10.1016/j.tcb.2014.07.001

APA

Zane, L., Sharma, V., & Misteli, T. (2014). Common features of chromatin in aging and cancer: Cause or coincidence? TRENDS IN CELL BIOLOGY, 24(11), 686-694. https://doi.org/10.1016/j.tcb.2014.07.001

Vancouver

Zane L, Sharma V, Misteli T. Common features of chromatin in aging and cancer: Cause or coincidence? TRENDS IN CELL BIOLOGY. 2014;24(11):686-694. https://doi.org/10.1016/j.tcb.2014.07.001

Author

Zane, Linda ; Sharma, Vivek ; Misteli, Tom. / Common features of chromatin in aging and cancer : Cause or coincidence?. In: TRENDS IN CELL BIOLOGY. 2014 ; Vol. 24, No. 11. pp. 686-694.

Bibtex - Download

@article{e03d900e1f6e46cba26ddf26bafe8f7e,
title = "Common features of chromatin in aging and cancer: Cause or coincidence?",
abstract = "Age is a major risk factor for cancer. Alterations in DNA methylation, histone modifications, chromatin structure, and epigenetic regulatory mechanisms are prominent hallmarks of both the aging process and cancer. Intriguingly - or possibly coincidentally - several chromatin features are common between aging and cancer. Here we ask whether, and if so how, aging-associated chromatin modifications contribute to tumor susceptibility and tumorigenesis.",
author = "Linda Zane and Vivek Sharma and Tom Misteli",
year = "2014",
doi = "10.1016/j.tcb.2014.07.001",
language = "English",
volume = "24",
pages = "686--694",
journal = "TRENDS IN CELL BIOLOGY",
issn = "0962-8924",
publisher = "Elsevier",
number = "11",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Common features of chromatin in aging and cancer

T2 - Cause or coincidence?

AU - Zane, Linda

AU - Sharma, Vivek

AU - Misteli, Tom

PY - 2014

Y1 - 2014

N2 - Age is a major risk factor for cancer. Alterations in DNA methylation, histone modifications, chromatin structure, and epigenetic regulatory mechanisms are prominent hallmarks of both the aging process and cancer. Intriguingly - or possibly coincidentally - several chromatin features are common between aging and cancer. Here we ask whether, and if so how, aging-associated chromatin modifications contribute to tumor susceptibility and tumorigenesis.

AB - Age is a major risk factor for cancer. Alterations in DNA methylation, histone modifications, chromatin structure, and epigenetic regulatory mechanisms are prominent hallmarks of both the aging process and cancer. Intriguingly - or possibly coincidentally - several chromatin features are common between aging and cancer. Here we ask whether, and if so how, aging-associated chromatin modifications contribute to tumor susceptibility and tumorigenesis.

UR - http://www.scopus.com/inward/record.url?scp=84927698872&partnerID=8YFLogxK

U2 - 10.1016/j.tcb.2014.07.001

DO - 10.1016/j.tcb.2014.07.001

M3 - Review Article

VL - 24

SP - 686

EP - 694

JO - TRENDS IN CELL BIOLOGY

JF - TRENDS IN CELL BIOLOGY

SN - 0962-8924

IS - 11

ER -