Tampere University of Technology

TUTCRIS Research Portal

Computational cancer biology: education is a natural key to many locks

Research output: Contribution to journalArticleScientificpeer-review

Details

Original languageEnglish
Article number7
JournalBMC Cancer
Volume15
Issue number1
DOIs
Publication statusPublished - 15 Jan 2015
Publication typeA1 Journal article-refereed

Abstract

Background: Oncology is a field that profits tremendously from the genomic data generated by high-throughput technologies, including next-generation sequencing. However, in order to exploit, integrate, visualize and interpret such high-dimensional data efficiently, non-trivial computational and statistical analysis methods are required that need to be developed in a problem-directed manner. Discussion: For this reason, computational cancer biology aims to fill this gap. Unfortunately, computational cancer biology is not yet fully recognized as a coequal field in oncology, leading to a delay in its maturation and, as an immediate consequence, an under-exploration of high-throughput data for translational research. Summary: Here we argue that this imbalance, favoring 'wet lab-based activities', will be naturally rectified over time, if the next generation of scientists receives an academic education that provides a fair and competent introduction to computational biology and its manifold capabilities. Furthermore, we discuss a number of local educational provisions that can be implemented on university level to help in facilitating the process of harmonization.

ASJC Scopus subject areas

Keywords

  • Cancer, Computational biology, Computational genomics, Computational oncology, Genomics data, Statistical genomics, Systems medicine