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Core-clad phosphate glass fibers for biosensing

Research output: Contribution to journalArticleScientificpeer-review

Details

Original languageEnglish
Pages (from-to)458 - 465
JournalMaterials Science and Engineering C: Materials for Biological Applications
Volume96
DOIs
Publication statusPublished - Mar 2019
Publication typeA1 Journal article-refereed

Abstract

Recently, a phosphate glass with composition 20 CaO-20 SrO-10 Na2O-50 P2O5 (mol%) was found to have good potential as a biomaterial and to possess thermal properties suitable for fiber drawing. This study opened the path towards the development of fully bioresorbable fibers promising for biosensing. In the past, this phosphate glass with CeO2 was found to increase the refractive index and the glass stability. Therefore, a new SrO-containing glass was prepared with 1 mol% of CeO2 and core fibers were drawn from it. A core-clad fiber was also processed, where the core was a Ce-doped glass and the clad undoped, to allow for total internal reflection. The mechanical properties of the core and core-clad fibers are discussed as a function of immersion time in TRIS-buffer solution. Finally, a sensing region was created, in the core-clad fiber, by etching the cladding using phosphoric acid. Then, the change in light transmission, upon immersion in TRIS-buffer solution, was quantified to assess the potential use of the novel core-clad fiber as a biosensor. Upon immersion in TRIS, the core-clad fiber was found to guide light effectively and to maintain a tensile strength of ~150–200 MPa up to 6 weeks in TRIS, clearly showing that this fiber has potential as a biosensing device.

Publication forum classification

Field of science, Statistics Finland