Direct Measurement of Contraction Force in Human Cardiac Tissue Model Using Piezoelectric Cantilever Sensor Technique
Research output: Contribution to journal › Article › Scientific › peer-review
|Number of pages||6|
|Journal||Current Applied Physics|
|Publication status||Accepted/In press - 25 Oct 2019|
|Publication type||A1 Journal article-refereed|
A proof-of-concept method for measuring cardiac tissue contraction force using an in-house-developed piezoelectric cantilever sensor system is demonstrated. Contracting forces of 7.2 to 16.6 μN were measured from a human cardiac tissue construct. Beating cardiac tissue constructs were monitored in-situ under a microscope during the contraction force measurements. Development of the measurement method allows very low forces such as the ones that appear in biological small scale systems to be determined.
- cardiomyocyte, piezoelectric sensor, cantilever, contraction force