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Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection

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Details

Original languageEnglish
Number of pages6
JournalGlobal Challenges
Volume3
Issue number2
Early online date12 Nov 2018
DOIs
Publication statusPublished - Feb 2019
Publication typeA1 Journal article-refereed

Abstract

Point-of-care devices that are inexpensive, disposable, and environmentally friendly are becoming increasingly predominant in the field of biosensing and biodiagnostics. Here, microfluidics is a suitable option to endow portability and minimal reagent and material consumption. Nanocellulose is introduced to manufacture microfluidic channels and as a storage and immobilization compartment of glucose oxidase. Improved enzymatic activity retention is demonstrated in a simple and disposable point-of-care diagnostic unit that is able to detect glucose from fluid matrices at 0.1 mM concentration and in less than 10 min. It is concluded that the patterning and fluidic technologies that are possible with nanocellulose enable easily scalable multianalyte designs.

Keywords

  • biosensors, colorimetry, diagnostics, glucose oxidase, nanofibrils

Publication forum classification

Field of science, Statistics Finland

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