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Effective Connectivity Analysis in Brain Networks: a GPU-Accelerated Implementation of the Cox Method

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Details

Original languageEnglish
Pages (from-to)1226-1237
Number of pages12
JournalIEEE Journal of Selected Topics in Signal Processing
Volume10
Issue number7
DOIs
Publication statusPublished - 24 Aug 2016
Publication typeA1 Journal article-refereed

Abstract

The observation of interactions between neurons of a network can reveal important information about how information is processed within that network. Such observation can be established with the analysis of causality between the activities of the different neurons in the network. This analysis is called effective connectivity analysis. However, methods for such analysis are either computationally heavy for daily use or too inaccurate for making reliable analyses. Cox method produces reliable analysis, but the computation takes hours on CPUs, making it slow to use on research. In this paper, two algorithms are presented that speed up analysis of Cox method by parallelizing the computation on a Graphical Processing Unit (GPU) with the help of Compute Unified Device Architecture (CUDA) platform. Both algorithms are evaluated according to network size and recording duration. The interest of proposing GPU implementations is in gaining computation time but another important interest is that such implementation requires rethinking the algorithm in different ways as the sequential implementation. This rethinking itself brings new optimization possibilities, e.g. by employing OpenCL. Utilizing this accelerated implementation, the Cox method is then applied on an experimental dataset from CRCNS in a personal computer. This should facilitate observations of biological neural network organizations that can provide new insights to improve understanding of memory, learning and intelligence.

Publication forum classification

Field of science, Statistics Finland