Tampere University of Technology

TUTCRIS Research Portal

Effects of percutaneous transluminal angioplasty of superficial femoral artery on photoplethysmographic pulse transit times

Research output: Contribution to journalArticleScientificpeer-review

Details

Original languageEnglish
Pages (from-to)1058-1065
JournalIEEE Journal of Biomedical and Health Informatics
Volume23
Issue number3
Early online date27 Jun 2018
DOIs
Publication statusPublished - May 2019
Publication typeA1 Journal article-refereed

Abstract

We analyze the changes in upper and lower limb pulse transit times (PTT) caused by peripheral artery disease (PAD) and its treatment with percutaneous transluminal angioplasty (PTA) of the superficial femoral artery. PTTs were extracted from the photoplethysmograms (PPG) recorded from an index finger and 2nd toes. PTTs were defined between the R-peaks of the ECG and different reference points of the (PPG): foot and peak points, maxima of 1st and 2nd derivative, and by means of intersecting tangents method. Also the PTTs between the toe and finger pulses were analyzed. Our sample consists of 24 subjects examined before and after the PTA and in 1-month follow-up visit. Also 28 older than 65 years controls having normal ankle-to-brachial pressure index (ABI) and no history in cardiovascular diseases as well as 21 younger subjects were examined. The differences between the groups and pre- and post-treatment phases were analyzed by means of non-parametric statistical tests. The changes in the PTTs of upper limb and non-treated lower limb were negligible. The agreement with the reference values, ABI and toe pressures, was studied by kappa-analysis, resulting in kappa-values of 0.33<formula><tex>$\times$</tex></formula>0.91. Differences in PTTs were found between pre-treatment state of the treated limb, post-treatment state and the follow-up visit, as well as between the pre-treatment state and controls. If patients' age and systolic blood pressure were taken into consideration, the method of lower limb PTT calculation from the peak point turns out feasible in finding the markers of PAD and monitoring post- treatment vascular remodellation.

Keywords

  • Atherosclerosis, Peripheral artery disease, Photoplethysmography, Pulse wave measurements

Publication forum classification

Field of science, Statistics Finland

Downloads statistics

No data available