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Extracellular Electrical Stimulation-based in Vitro Neuroscience: A Minireview of Methods and a Paradigm Shift Proposal

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Details

Original languageEnglish
Title of host publication2019 26th IEEE International Conference on Electronics, Circuits and Systems (ICECS)
PublisherIEEE
Pages883-886
Number of pages4
ISBN (Electronic)978-1-7281-0996-1
ISBN (Print)978-1-7281-0997-8
DOIs
Publication statusPublished - Nov 2019
Publication typeA4 Article in a conference publication
EventIEEE International Conference on Electronics, Circuits and Systems -
Duration: 31 Dec 1899 → …

Conference

ConferenceIEEE International Conference on Electronics, Circuits and Systems
Period31/12/99 → …

Abstract

Biological neuronal cells communicate using neurochemistry and electrical signals. Electrical stimulation (ES) is utilized to study neuronal cells and networks. Currently, ES is applied and responses observed in an open-loop fashion, which does not resemble natural network I/O. We hypothesize that real-time closed-loop full-duplex (simultaneous two-way) paradigms could provide deeper insight in natural neuronal networks, helping to understand our brains and to control neuronal network states to cure diseases. We present a minireview of ES-based extracellular in vitro neuroscience, our first long-term closed-loop ES experiment results as the proof-of-feasibility of the method, and our paradigm-shifting proposal of dialogical bio-ICT paradigms.

Keywords

  • bio-ICT interaction, biological neuronal networks, closed-loop control, DSP, electrical stimulation, open-loop control, real-time

Publication forum classification