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How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI

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How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI. / Pajula, Juha; Tohka, Jussi.

In: Computational Intelligence and Neuroscience, Vol. 2016, 2094601, 2016.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Pajula, J & Tohka, J 2016, 'How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI', Computational Intelligence and Neuroscience, vol. 2016, 2094601. https://doi.org/10.1155/2016/2094601

APA

Pajula, J., & Tohka, J. (2016). How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI. Computational Intelligence and Neuroscience, 2016, [2094601]. https://doi.org/10.1155/2016/2094601

Vancouver

Pajula J, Tohka J. How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI. Computational Intelligence and Neuroscience. 2016;2016. 2094601. https://doi.org/10.1155/2016/2094601

Author

Pajula, Juha ; Tohka, Jussi. / How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI. In: Computational Intelligence and Neuroscience. 2016 ; Vol. 2016.

Bibtex - Download

@article{ef3419d2cd7648ec8afbbde0c6bc03ef,
title = "How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI",
abstract = "Inter-subject correlation (ISC) is a widely used method for analyzing functional magnetic resonance imaging (fMRI) data acquired during naturalistic stimuli. A challenge in ISC analysis is to define the required sample size in the way that the results are reliable. We studied the effect of the sample size on the reliability of ISC analysis and additionally addressed the following question: How many subjects are needed for the ISC statistics to converge to the ISC statistics obtained using a large sample? The study was realized using a large block design data set of 130 subjects. We performed a split-half resampling based analysis repeatedly sampling two nonoverlapping subsets of 10-65 subjects and comparing the ISC maps between the independent subject sets. Our findings suggested that with 20 subjects, on average, the ISC statistics had converged close to a large sample ISC statistic with 130 subjects. However, the split-half reliability of unthresholded and thresholded ISC maps improved notably when the number of subjects was increased from 20 to 30 or more.",
author = "Juha Pajula and Jussi Tohka",
note = "EXT={"}Tohka, Jussi{"}",
year = "2016",
doi = "10.1155/2016/2094601",
language = "English",
volume = "2016",
journal = "Computational Intelligence and Neuroscience",
issn = "1687-5273",
publisher = "Hindawi Publishing Corporation",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - How Many Is Enough? Effect of Sample Size in Inter-Subject Correlation Analysis of fMRI

AU - Pajula, Juha

AU - Tohka, Jussi

N1 - EXT="Tohka, Jussi"

PY - 2016

Y1 - 2016

N2 - Inter-subject correlation (ISC) is a widely used method for analyzing functional magnetic resonance imaging (fMRI) data acquired during naturalistic stimuli. A challenge in ISC analysis is to define the required sample size in the way that the results are reliable. We studied the effect of the sample size on the reliability of ISC analysis and additionally addressed the following question: How many subjects are needed for the ISC statistics to converge to the ISC statistics obtained using a large sample? The study was realized using a large block design data set of 130 subjects. We performed a split-half resampling based analysis repeatedly sampling two nonoverlapping subsets of 10-65 subjects and comparing the ISC maps between the independent subject sets. Our findings suggested that with 20 subjects, on average, the ISC statistics had converged close to a large sample ISC statistic with 130 subjects. However, the split-half reliability of unthresholded and thresholded ISC maps improved notably when the number of subjects was increased from 20 to 30 or more.

AB - Inter-subject correlation (ISC) is a widely used method for analyzing functional magnetic resonance imaging (fMRI) data acquired during naturalistic stimuli. A challenge in ISC analysis is to define the required sample size in the way that the results are reliable. We studied the effect of the sample size on the reliability of ISC analysis and additionally addressed the following question: How many subjects are needed for the ISC statistics to converge to the ISC statistics obtained using a large sample? The study was realized using a large block design data set of 130 subjects. We performed a split-half resampling based analysis repeatedly sampling two nonoverlapping subsets of 10-65 subjects and comparing the ISC maps between the independent subject sets. Our findings suggested that with 20 subjects, on average, the ISC statistics had converged close to a large sample ISC statistic with 130 subjects. However, the split-half reliability of unthresholded and thresholded ISC maps improved notably when the number of subjects was increased from 20 to 30 or more.

U2 - 10.1155/2016/2094601

DO - 10.1155/2016/2094601

M3 - Article

VL - 2016

JO - Computational Intelligence and Neuroscience

JF - Computational Intelligence and Neuroscience

SN - 1687-5273

M1 - 2094601

ER -