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Intrapleural photodynamic therapy for mesothelioma: What place and which future?

Research output: Contribution to journalReview ArticleScientificpeer-review


Original languageEnglish
Pages (from-to)2237-2245
Number of pages9
JournalAnnals of Thoracic Surgery
Issue number6
Publication statusPublished - 1 Jun 2015
Publication typeA2 Review article in a scientific journal


In the surgical multimodal management of malignant pleural mesothelioma, it seems crucial to proceed with an efficient local adjuvant treatment to kill residual tumor cells. Intrapleural photodynamic therapy has recently emerged as a potential candidate in this goal. In this review, we analyzed and classified 16 articles in which patients with malignant pleural mesothelioma received intrapleural photodynamic therapy after maximal surgical resection. The toxicity, effect on survival, and development of the technique were assessed. After two decades of clinical studies, intrapleural photodynamic therapy after surgical resection became a safe treatment that significantly improved the survival of patients.