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Iron overload of hematological origin: validation of a screening procedure for cardiac overload by MRI in routine clinical practice.

Research output: Contribution to journalArticleScientificpeer-review

Standard

Iron overload of hematological origin : validation of a screening procedure for cardiac overload by MRI in routine clinical practice. / Ernst, O.; Thuret, I.; Petit, P.; Ameur, F.; Loundou, A. D.; de Kerviler, E.; Izzillo, R.; Willig, A. L.; Pascal, L.; Verlhac, S.; Mordon, S.; Fenaux, P.; Rose, C.

In: Diagnostic and interventional imaging, Vol. 94, No. 6, 06.2013, p. 601-608.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Ernst, O, Thuret, I, Petit, P, Ameur, F, Loundou, AD, de Kerviler, E, Izzillo, R, Willig, AL, Pascal, L, Verlhac, S, Mordon, S, Fenaux, P & Rose, C 2013, 'Iron overload of hematological origin: validation of a screening procedure for cardiac overload by MRI in routine clinical practice.', Diagnostic and interventional imaging, vol. 94, no. 6, pp. 601-608.

APA

Ernst, O., Thuret, I., Petit, P., Ameur, F., Loundou, A. D., de Kerviler, E., ... Rose, C. (2013). Iron overload of hematological origin: validation of a screening procedure for cardiac overload by MRI in routine clinical practice. Diagnostic and interventional imaging, 94(6), 601-608.

Vancouver

Ernst O, Thuret I, Petit P, Ameur F, Loundou AD, de Kerviler E et al. Iron overload of hematological origin: validation of a screening procedure for cardiac overload by MRI in routine clinical practice. Diagnostic and interventional imaging. 2013 Jun;94(6):601-608.

Author

Ernst, O. ; Thuret, I. ; Petit, P. ; Ameur, F. ; Loundou, A. D. ; de Kerviler, E. ; Izzillo, R. ; Willig, A. L. ; Pascal, L. ; Verlhac, S. ; Mordon, S. ; Fenaux, P. ; Rose, C. / Iron overload of hematological origin : validation of a screening procedure for cardiac overload by MRI in routine clinical practice. In: Diagnostic and interventional imaging. 2013 ; Vol. 94, No. 6. pp. 601-608.

Bibtex - Download

@article{0936c6c34c6b42e3ad8cad160c5947b9,
title = "Iron overload of hematological origin: validation of a screening procedure for cardiac overload by MRI in routine clinical practice.",
abstract = "Screening for cardiac iron overload is generally done by magnetic resonance imaging (MRI) and demonstrated by a shortening of the myocardial T2* below 20 ms at 1.5 Tesla. This measurement was validated with a specific sequence and the CMRTools({\circledR}) calculation software (reference technique). The objective of this study was to validate the use of sequences and software programs that are available in routine clinical practice to screen for iron overload. First, a phantom of 11 tubes with a T2* between 4 and 33 ms was tested at three sites that had MRI machines of different brands. Second, the myocardial T2* values of 75 patients were measured in routine clinical practice using two methods. The first method used the reference sequence specially installed in the machines associated with the CMRTool software. The second method used the standard acquisition sequences available in the machines followed by calculation on a computer spreadsheet. In the phantom, the mean of the differences in T2* between each machine was 0.6 ms. Thirteen patients had a lowered T2* value with the reference technique. Three cases were poorly classified using the routine technique and corresponded with false positives of low overload (T2* between 18 and 20 ms). Screening for myocardial iron overload can be done by MRI by using sequences and calculation software available in routine clinical practice during the same examination as the one for the evaluation of hepatic iron overload.",
author = "O. Ernst and I. Thuret and P. Petit and F. Ameur and Loundou, {A. D.} and {de Kerviler}, E. and R. Izzillo and Willig, {A. L.} and L. Pascal and S. Verlhac and S. Mordon and P. Fenaux and C. Rose",
year = "2013",
month = "6",
language = "English",
volume = "94",
pages = "601--608",
journal = "Diagnostic and interventional imaging",
issn = "2211-5684",
publisher = "Elsevier",
number = "6",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Iron overload of hematological origin

T2 - validation of a screening procedure for cardiac overload by MRI in routine clinical practice.

AU - Ernst, O.

AU - Thuret, I.

AU - Petit, P.

AU - Ameur, F.

AU - Loundou, A. D.

AU - de Kerviler, E.

AU - Izzillo, R.

AU - Willig, A. L.

AU - Pascal, L.

AU - Verlhac, S.

AU - Mordon, S.

AU - Fenaux, P.

AU - Rose, C.

PY - 2013/6

Y1 - 2013/6

N2 - Screening for cardiac iron overload is generally done by magnetic resonance imaging (MRI) and demonstrated by a shortening of the myocardial T2* below 20 ms at 1.5 Tesla. This measurement was validated with a specific sequence and the CMRTools(®) calculation software (reference technique). The objective of this study was to validate the use of sequences and software programs that are available in routine clinical practice to screen for iron overload. First, a phantom of 11 tubes with a T2* between 4 and 33 ms was tested at three sites that had MRI machines of different brands. Second, the myocardial T2* values of 75 patients were measured in routine clinical practice using two methods. The first method used the reference sequence specially installed in the machines associated with the CMRTool software. The second method used the standard acquisition sequences available in the machines followed by calculation on a computer spreadsheet. In the phantom, the mean of the differences in T2* between each machine was 0.6 ms. Thirteen patients had a lowered T2* value with the reference technique. Three cases were poorly classified using the routine technique and corresponded with false positives of low overload (T2* between 18 and 20 ms). Screening for myocardial iron overload can be done by MRI by using sequences and calculation software available in routine clinical practice during the same examination as the one for the evaluation of hepatic iron overload.

AB - Screening for cardiac iron overload is generally done by magnetic resonance imaging (MRI) and demonstrated by a shortening of the myocardial T2* below 20 ms at 1.5 Tesla. This measurement was validated with a specific sequence and the CMRTools(®) calculation software (reference technique). The objective of this study was to validate the use of sequences and software programs that are available in routine clinical practice to screen for iron overload. First, a phantom of 11 tubes with a T2* between 4 and 33 ms was tested at three sites that had MRI machines of different brands. Second, the myocardial T2* values of 75 patients were measured in routine clinical practice using two methods. The first method used the reference sequence specially installed in the machines associated with the CMRTool software. The second method used the standard acquisition sequences available in the machines followed by calculation on a computer spreadsheet. In the phantom, the mean of the differences in T2* between each machine was 0.6 ms. Thirteen patients had a lowered T2* value with the reference technique. Three cases were poorly classified using the routine technique and corresponded with false positives of low overload (T2* between 18 and 20 ms). Screening for myocardial iron overload can be done by MRI by using sequences and calculation software available in routine clinical practice during the same examination as the one for the evaluation of hepatic iron overload.

UR - http://www.scopus.com/inward/record.url?scp=84895848508&partnerID=8YFLogxK

M3 - Article

VL - 94

SP - 601

EP - 608

JO - Diagnostic and interventional imaging

JF - Diagnostic and interventional imaging

SN - 2211-5684

IS - 6

ER -