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Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy

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Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy. / Nevalainen, Olli; Auvinen, Anssi; Ansakorpi, Hanna; Artama, Miia; Raitanen, Jani; Isojärvi, Jouko.

In: EPILEPSIA, Vol. 53, No. 12, 12.2012.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Nevalainen, O, Auvinen, A, Ansakorpi, H, Artama, M, Raitanen, J & Isojärvi, J 2012, 'Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy', EPILEPSIA, vol. 53, no. 12. https://doi.org/10.1111/epi.12006

APA

Nevalainen, O., Auvinen, A., Ansakorpi, H., Artama, M., Raitanen, J., & Isojärvi, J. (2012). Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy. EPILEPSIA, 53(12). https://doi.org/10.1111/epi.12006

Vancouver

Nevalainen O, Auvinen A, Ansakorpi H, Artama M, Raitanen J, Isojärvi J. Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy. EPILEPSIA. 2012 Dec;53(12). https://doi.org/10.1111/epi.12006

Author

Nevalainen, Olli ; Auvinen, Anssi ; Ansakorpi, Hanna ; Artama, Miia ; Raitanen, Jani ; Isojärvi, Jouko. / Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy. In: EPILEPSIA. 2012 ; Vol. 53, No. 12.

Bibtex - Download

@article{8646fba50fc546adb1756e6a66630c3e,
title = "Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy",
abstract = "The authors evaluated the contribution of various clinical characteristics to mortality risk and underlying causes of death among all adult patients with epilepsy seen at the Department of Neurology, Oulu University Hospital in Finland during 1996 and 1997. Hazard ratios (HRs) for mortality in 1998-2006 relative to a population-based reference cohort were estimated using Cox modeling, with adjustment for age and gender. The HR for total mortality was 2.66 (95{\%} confidence interval [CI] 2.09-3.39). Infectious etiology of epilepsy (HR 5.77, 95{\%} CI 2.52-13.2) and a seizure frequency of ≥1 per month (HR 4.42, 95{\%} CI 3.00-6.52) related to high risks of death. Cancer (21{\%}), ischemic heart disease (15{\%}), and accidents (12{\%}) caused most of the potential years of life lost. Despite recent advances in treatment of epilepsy and improved seizure control, chronic epilepsy still carries a substantially increased risk of death.",
keywords = "Epilepsy, Finland, Mortality, Potential years of life lost, Survival",
author = "Olli Nevalainen and Anssi Auvinen and Hanna Ansakorpi and Miia Artama and Jani Raitanen and Jouko Isoj{\"a}rvi",
year = "2012",
month = "12",
doi = "10.1111/epi.12006",
language = "English",
volume = "53",
journal = "EPILEPSIA",
issn = "0013-9580",
publisher = "Wiley",
number = "12",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Mortality by clinical characteristics in a tertiary care cohort of adult patients with chronic epilepsy

AU - Nevalainen, Olli

AU - Auvinen, Anssi

AU - Ansakorpi, Hanna

AU - Artama, Miia

AU - Raitanen, Jani

AU - Isojärvi, Jouko

PY - 2012/12

Y1 - 2012/12

N2 - The authors evaluated the contribution of various clinical characteristics to mortality risk and underlying causes of death among all adult patients with epilepsy seen at the Department of Neurology, Oulu University Hospital in Finland during 1996 and 1997. Hazard ratios (HRs) for mortality in 1998-2006 relative to a population-based reference cohort were estimated using Cox modeling, with adjustment for age and gender. The HR for total mortality was 2.66 (95% confidence interval [CI] 2.09-3.39). Infectious etiology of epilepsy (HR 5.77, 95% CI 2.52-13.2) and a seizure frequency of ≥1 per month (HR 4.42, 95% CI 3.00-6.52) related to high risks of death. Cancer (21%), ischemic heart disease (15%), and accidents (12%) caused most of the potential years of life lost. Despite recent advances in treatment of epilepsy and improved seizure control, chronic epilepsy still carries a substantially increased risk of death.

AB - The authors evaluated the contribution of various clinical characteristics to mortality risk and underlying causes of death among all adult patients with epilepsy seen at the Department of Neurology, Oulu University Hospital in Finland during 1996 and 1997. Hazard ratios (HRs) for mortality in 1998-2006 relative to a population-based reference cohort were estimated using Cox modeling, with adjustment for age and gender. The HR for total mortality was 2.66 (95% confidence interval [CI] 2.09-3.39). Infectious etiology of epilepsy (HR 5.77, 95% CI 2.52-13.2) and a seizure frequency of ≥1 per month (HR 4.42, 95% CI 3.00-6.52) related to high risks of death. Cancer (21%), ischemic heart disease (15%), and accidents (12%) caused most of the potential years of life lost. Despite recent advances in treatment of epilepsy and improved seizure control, chronic epilepsy still carries a substantially increased risk of death.

KW - Epilepsy

KW - Finland

KW - Mortality

KW - Potential years of life lost

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=84870602397&partnerID=8YFLogxK

U2 - 10.1111/epi.12006

DO - 10.1111/epi.12006

M3 - Article

VL - 53

JO - EPILEPSIA

JF - EPILEPSIA

SN - 0013-9580

IS - 12

ER -