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New design of textile light diffusers for photodynamic therapy

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New design of textile light diffusers for photodynamic therapy. / Cochrane, Cédric; Mordon, Serge R.; Lesage, Jean Claude; Koncar, Vladan.

In: Materials Science and Engineering C: Materials for Biological Applications, Vol. 33, No. 3, 01.04.2013, p. 1170-1175.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Cochrane, C, Mordon, SR, Lesage, JC & Koncar, V 2013, 'New design of textile light diffusers for photodynamic therapy', Materials Science and Engineering C: Materials for Biological Applications, vol. 33, no. 3, pp. 1170-1175. https://doi.org/10.1016/j.msec.2012.12.007

APA

Cochrane, C., Mordon, S. R., Lesage, J. C., & Koncar, V. (2013). New design of textile light diffusers for photodynamic therapy. Materials Science and Engineering C: Materials for Biological Applications, 33(3), 1170-1175. https://doi.org/10.1016/j.msec.2012.12.007

Vancouver

Cochrane C, Mordon SR, Lesage JC, Koncar V. New design of textile light diffusers for photodynamic therapy. Materials Science and Engineering C: Materials for Biological Applications. 2013 Apr 1;33(3):1170-1175. https://doi.org/10.1016/j.msec.2012.12.007

Author

Cochrane, Cédric ; Mordon, Serge R. ; Lesage, Jean Claude ; Koncar, Vladan. / New design of textile light diffusers for photodynamic therapy. In: Materials Science and Engineering C: Materials for Biological Applications. 2013 ; Vol. 33, No. 3. pp. 1170-1175.

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@article{215712205713410c9ff54843596657ee,
title = "New design of textile light diffusers for photodynamic therapy",
abstract = "A homogeneous and reproducible fluence delivery rate during clinical photodynamic therapy (PDT) plays a determinant role in preventing under- or overtreatment. PDT applied in dermatology has been carried out with a wide variety of light sources delivering a broad range of more or less adapted light doses. Due to the complexities of the human anatomy, these light sources do not in fact deliver a uniform light distribution to the skin. Therefore, the development of flexible light sources would considerably improve the homogeneity of light delivery. The integration of plastic optical fiber (POF) into textile structures could offer an interesting alternative. In this article, a textile light diffuser (TLD) has been developed using POF and Polyester yarns. Predetermined POF macrobending leads to side emission of light when the critical angle is exceeded. Therefore, a specific pattern based on different satin weaves has been developed in order to improve light emission homogeneity and to correct the decrease of side emitted radiation intensity along POF. The prototyped fabrics (approximately 100 cm2: 5 × 20 cm) were woven using a hand loom, then both ends of the POF were coupled to a laser diode (5 W, 635 nm). The fluence rate (mW/cm2) and the homogeneity of light delivery by the TLD were evaluated. Temperature evolution, as a function of time, was controlled with an infrared thermographic camera. When using a power source of 5 W, the fluence rate of the TLD was 18 ± 2.5 mw/cm 2. Due to the high efficiency of the TLD, the optical losses were very low. The TLD temperature elevation was 0.6 C after 10 min of illumination. Our TLD meets the basic requirements for PDT: homogeneous light distribution and flexibility. It also proves that large (500 cm2) textile light diffusers adapted to skin, but also to peritoneal or pleural cavity, PDTs can be easily produced by textile manufacturing processes.",
keywords = "Laser, Optical fiber, Photodynamic therapy, Textile light diffuser, Weaving",
author = "C{\'e}dric Cochrane and Mordon, {Serge R.} and Lesage, {Jean Claude} and Vladan Koncar",
year = "2013",
month = "4",
day = "1",
doi = "10.1016/j.msec.2012.12.007",
language = "English",
volume = "33",
pages = "1170--1175",
journal = "Materials Science and Engineering C: Materials for Biological Applications",
issn = "0928-4931",
publisher = "Elsevier",
number = "3",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - New design of textile light diffusers for photodynamic therapy

AU - Cochrane, Cédric

AU - Mordon, Serge R.

AU - Lesage, Jean Claude

AU - Koncar, Vladan

PY - 2013/4/1

Y1 - 2013/4/1

N2 - A homogeneous and reproducible fluence delivery rate during clinical photodynamic therapy (PDT) plays a determinant role in preventing under- or overtreatment. PDT applied in dermatology has been carried out with a wide variety of light sources delivering a broad range of more or less adapted light doses. Due to the complexities of the human anatomy, these light sources do not in fact deliver a uniform light distribution to the skin. Therefore, the development of flexible light sources would considerably improve the homogeneity of light delivery. The integration of plastic optical fiber (POF) into textile structures could offer an interesting alternative. In this article, a textile light diffuser (TLD) has been developed using POF and Polyester yarns. Predetermined POF macrobending leads to side emission of light when the critical angle is exceeded. Therefore, a specific pattern based on different satin weaves has been developed in order to improve light emission homogeneity and to correct the decrease of side emitted radiation intensity along POF. The prototyped fabrics (approximately 100 cm2: 5 × 20 cm) were woven using a hand loom, then both ends of the POF were coupled to a laser diode (5 W, 635 nm). The fluence rate (mW/cm2) and the homogeneity of light delivery by the TLD were evaluated. Temperature evolution, as a function of time, was controlled with an infrared thermographic camera. When using a power source of 5 W, the fluence rate of the TLD was 18 ± 2.5 mw/cm 2. Due to the high efficiency of the TLD, the optical losses were very low. The TLD temperature elevation was 0.6 C after 10 min of illumination. Our TLD meets the basic requirements for PDT: homogeneous light distribution and flexibility. It also proves that large (500 cm2) textile light diffusers adapted to skin, but also to peritoneal or pleural cavity, PDTs can be easily produced by textile manufacturing processes.

AB - A homogeneous and reproducible fluence delivery rate during clinical photodynamic therapy (PDT) plays a determinant role in preventing under- or overtreatment. PDT applied in dermatology has been carried out with a wide variety of light sources delivering a broad range of more or less adapted light doses. Due to the complexities of the human anatomy, these light sources do not in fact deliver a uniform light distribution to the skin. Therefore, the development of flexible light sources would considerably improve the homogeneity of light delivery. The integration of plastic optical fiber (POF) into textile structures could offer an interesting alternative. In this article, a textile light diffuser (TLD) has been developed using POF and Polyester yarns. Predetermined POF macrobending leads to side emission of light when the critical angle is exceeded. Therefore, a specific pattern based on different satin weaves has been developed in order to improve light emission homogeneity and to correct the decrease of side emitted radiation intensity along POF. The prototyped fabrics (approximately 100 cm2: 5 × 20 cm) were woven using a hand loom, then both ends of the POF were coupled to a laser diode (5 W, 635 nm). The fluence rate (mW/cm2) and the homogeneity of light delivery by the TLD were evaluated. Temperature evolution, as a function of time, was controlled with an infrared thermographic camera. When using a power source of 5 W, the fluence rate of the TLD was 18 ± 2.5 mw/cm 2. Due to the high efficiency of the TLD, the optical losses were very low. The TLD temperature elevation was 0.6 C after 10 min of illumination. Our TLD meets the basic requirements for PDT: homogeneous light distribution and flexibility. It also proves that large (500 cm2) textile light diffusers adapted to skin, but also to peritoneal or pleural cavity, PDTs can be easily produced by textile manufacturing processes.

KW - Laser

KW - Optical fiber

KW - Photodynamic therapy

KW - Textile light diffuser

KW - Weaving

UR - http://www.scopus.com/inward/record.url?scp=84873414524&partnerID=8YFLogxK

U2 - 10.1016/j.msec.2012.12.007

DO - 10.1016/j.msec.2012.12.007

M3 - Article

VL - 33

SP - 1170

EP - 1175

JO - Materials Science and Engineering C: Materials for Biological Applications

JF - Materials Science and Engineering C: Materials for Biological Applications

SN - 0928-4931

IS - 3

ER -