Non-coding RNAs in DNA damage and repair
Research output: Contribution to journal › Review Article › Scientific › peer-review
|Number of pages||8|
|Publication status||Published - 27 Jun 2013|
|Publication type||A2 Review article in a scientific journal|
Non-coding RNAs (ncRNAs) are increasingly recognized as central players in diverse biological processes. Upon DNA damage, the DNA damage response (DDR) elicits a complex signaling cascade, which includes the induction of multiple ncRNA species. Recent studies indicate that DNA-damage induced ncRNAs contribute to regulation of cell cycle, apoptosis and DNA repair, and thus play a key role in maintaining genome stability. This review summarizes the emerging role of ncRNAs in DNA damage and repair.