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Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy

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Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. / Tunninen, V.; Kauppinen, T.; Eskola, H.

EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017. Springer Verlag, 2018. p. 847-851 (IFMBE Proceedings; Vol. 65).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Harvard

Tunninen, V, Kauppinen, T & Eskola, H 2018, Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. in EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017. IFMBE Proceedings, vol. 65, Springer Verlag, pp. 847-851, Joint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), 1/01/00. https://doi.org/10.1007/978-981-10-5122-7_212

APA

Tunninen, V., Kauppinen, T., & Eskola, H. (2018). Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. In EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017 (pp. 847-851). (IFMBE Proceedings; Vol. 65). Springer Verlag. https://doi.org/10.1007/978-981-10-5122-7_212

Vancouver

Tunninen V, Kauppinen T, Eskola H. Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. In EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017. Springer Verlag. 2018. p. 847-851. (IFMBE Proceedings). https://doi.org/10.1007/978-981-10-5122-7_212

Author

Tunninen, V. ; Kauppinen, T. ; Eskola, H. / Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017. Springer Verlag, 2018. pp. 847-851 (IFMBE Proceedings).

Bibtex - Download

@inproceedings{24f15503171043418de083df03874650,
title = "Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy",
abstract = "The purpose of this study was to optimize effective, but technically challenging99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. An anthropomorphic parathyroid phantom was set up using a small sphere, a thyroid phantom and a thorax phantom with clinical range of activities of123I and99mTc. SPECT/CT acquisitions were performed using three collimators (Low Energy High Resolution (LEHR), Low Energy Ultra High Resolution (LEUHR) and Medium Energy Low Penetration (MELP)) and two energy window settings. Images were reconstructed with a combination of four different numbers of iterations and with or without scatter correction. Images were subjected to visual and quantitative evaluation. The effect of collimator, energy window selection and reconstruction parameters had a significant effect on visual appearance and adenoma contrast in parathyroid99mTc-sestamibi/123I subtraction SPECT/CT. Symmetrical energy windows and ultra-high resolution collimator yielded best results with some improvement with scatter correction.",
keywords = "Dual-isotope, Optimization, Parathyroid, Phantom, SPECT/CT",
author = "V. Tunninen and T. Kauppinen and H. Eskola",
note = "jufoid=58152 EXT={"}Tunninen, V.{"}",
year = "2018",
doi = "10.1007/978-981-10-5122-7_212",
language = "English",
isbn = "9789811051210",
series = "IFMBE Proceedings",
publisher = "Springer Verlag",
pages = "847--851",
booktitle = "EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017",
address = "Germany",

}

RIS (suitable for import to EndNote) - Download

TY - GEN

T1 - Optimization of99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy

AU - Tunninen, V.

AU - Kauppinen, T.

AU - Eskola, H.

N1 - jufoid=58152 EXT="Tunninen, V."

PY - 2018

Y1 - 2018

N2 - The purpose of this study was to optimize effective, but technically challenging99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. An anthropomorphic parathyroid phantom was set up using a small sphere, a thyroid phantom and a thorax phantom with clinical range of activities of123I and99mTc. SPECT/CT acquisitions were performed using three collimators (Low Energy High Resolution (LEHR), Low Energy Ultra High Resolution (LEUHR) and Medium Energy Low Penetration (MELP)) and two energy window settings. Images were reconstructed with a combination of four different numbers of iterations and with or without scatter correction. Images were subjected to visual and quantitative evaluation. The effect of collimator, energy window selection and reconstruction parameters had a significant effect on visual appearance and adenoma contrast in parathyroid99mTc-sestamibi/123I subtraction SPECT/CT. Symmetrical energy windows and ultra-high resolution collimator yielded best results with some improvement with scatter correction.

AB - The purpose of this study was to optimize effective, but technically challenging99mTc-sestamibi/123I subtraction SPECT/CT protocol for parathyroid scintigraphy. An anthropomorphic parathyroid phantom was set up using a small sphere, a thyroid phantom and a thorax phantom with clinical range of activities of123I and99mTc. SPECT/CT acquisitions were performed using three collimators (Low Energy High Resolution (LEHR), Low Energy Ultra High Resolution (LEUHR) and Medium Energy Low Penetration (MELP)) and two energy window settings. Images were reconstructed with a combination of four different numbers of iterations and with or without scatter correction. Images were subjected to visual and quantitative evaluation. The effect of collimator, energy window selection and reconstruction parameters had a significant effect on visual appearance and adenoma contrast in parathyroid99mTc-sestamibi/123I subtraction SPECT/CT. Symmetrical energy windows and ultra-high resolution collimator yielded best results with some improvement with scatter correction.

KW - Dual-isotope

KW - Optimization

KW - Parathyroid

KW - Phantom

KW - SPECT/CT

U2 - 10.1007/978-981-10-5122-7_212

DO - 10.1007/978-981-10-5122-7_212

M3 - Conference contribution

SN - 9789811051210

T3 - IFMBE Proceedings

SP - 847

EP - 851

BT - EMBEC and NBC 2017 - Joint Conference of the European Medical and Biological Engineering Conference EMBEC 2017 and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics, NBC 2017

PB - Springer Verlag

ER -