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Polypyrrole-coated electrodes show thickness-dependent stability in different conditions during 42-day follow-up in vitro

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Details

Original languageEnglish
Pages (from-to)2202-2213
Number of pages12
JournalJournal of Biomedical Materials Research. Part B: Applied Biomaterials
Volume106
Issue number6
Early online date23 Oct 2017
DOIs
Publication statusPublished - Aug 2018
Publication typeA1 Journal article-refereed

Abstract

Electroconductive polypyrrole/dodecylbenzenesulphonate (PPy/DBS) has been proposed as novel electrode coating for biomedical applications. However, as yet, little is known about its long-term stability in moist conditions. This study compares the stability of PPy/DBS-coated platinum electrodes that are either dry-stored, incubated, or both incubated and electrically stimulated. The electrical and material properties of three different coating thicknesses were monitored for 42 days. Initially, the PPy/DBS-coating decreased the low frequency impedance of the platinum electrodes by 52% to 79%. The dry-stored electrodes remained stable during the follow-up, whereas the properties of all the incubated electrodes were altered in three stages with thickness-dependent duration: stabilization, stable, and degradation. The coated electrodes would be applicable for short-term, low-frequency in vitro measurements of up to 14 days without electrical stimulation, and up to 7 days with stimulation. The coating thickness is bound to other coating properties, and should therefore be selected according to the specific target application. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2017.

Keywords

  • Journal Article

Publication forum classification

Field of science, Statistics Finland