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Possible strategy to use differential mobility spectrometry in real time applications

Research output: Contribution to journalArticleScientificpeer-review

Details

Original languageEnglish
JournalInternational Journal for Ion Mobility Spectrometry
DOIs
Publication statusE-pub ahead of print - 2019
Publication typeA1 Journal article-refereed

Abstract

Differential Mobility Spectrometry (DMS), also called as FAIMS is a variation of atmospheric pressure ion mobility measurement techniques and is capable of providing information about the electric field - mobility dependence of ions. In this method, a combined electric field is used. This field consists of asymmetric oscillating electric field of high intensity and low static field component. Analytical information in DMS is 2-dimensional dependence of ionic current on oscillating field amplitude and the value of static field intensity. The measurement of DMS signal for whole ranges of both variables is time consuming and also generates lot of data. It is a disadvantage of DMS method, which limits the use of this otherwise powerful technology in real time applications that require a response time of few seconds. This paper presents a way to limit measurement time by heuristic knowledge of the properties of the data space and another method based on the concept of Shannon Entropy to find operating parameters satisfying both separation and signal to noise ratio requirements.

ASJC Scopus subject areas

Keywords

  • Differential mobility spectrometry, DMS, FAIMS, Shannon entropy

Publication forum classification

Field of science, Statistics Finland