Possible strategy to use differential mobility spectrometry in real time applications
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Possible strategy to use differential mobility spectrometry in real time applications. / Anttalainen, Osmo; Puton, Jaroslaw; Kontunen, Anton; Karjalainen, Markus; Kumpulainen, Pekka; Oksala, Niku; Safaei, Zahra; Roine, Antti.
In: International Journal for Ion Mobility Spectrometry, 2019.Research output: Contribution to journal › Article › Scientific › peer-review
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TY - JOUR
T1 - Possible strategy to use differential mobility spectrometry in real time applications
AU - Anttalainen, Osmo
AU - Puton, Jaroslaw
AU - Kontunen, Anton
AU - Karjalainen, Markus
AU - Kumpulainen, Pekka
AU - Oksala, Niku
AU - Safaei, Zahra
AU - Roine, Antti
PY - 2019
Y1 - 2019
N2 - Differential Mobility Spectrometry (DMS), also called as FAIMS is a variation of atmospheric pressure ion mobility measurement techniques and is capable of providing information about the electric field - mobility dependence of ions. In this method, a combined electric field is used. This field consists of asymmetric oscillating electric field of high intensity and low static field component. Analytical information in DMS is 2-dimensional dependence of ionic current on oscillating field amplitude and the value of static field intensity. The measurement of DMS signal for whole ranges of both variables is time consuming and also generates lot of data. It is a disadvantage of DMS method, which limits the use of this otherwise powerful technology in real time applications that require a response time of few seconds. This paper presents a way to limit measurement time by heuristic knowledge of the properties of the data space and another method based on the concept of Shannon Entropy to find operating parameters satisfying both separation and signal to noise ratio requirements.
AB - Differential Mobility Spectrometry (DMS), also called as FAIMS is a variation of atmospheric pressure ion mobility measurement techniques and is capable of providing information about the electric field - mobility dependence of ions. In this method, a combined electric field is used. This field consists of asymmetric oscillating electric field of high intensity and low static field component. Analytical information in DMS is 2-dimensional dependence of ionic current on oscillating field amplitude and the value of static field intensity. The measurement of DMS signal for whole ranges of both variables is time consuming and also generates lot of data. It is a disadvantage of DMS method, which limits the use of this otherwise powerful technology in real time applications that require a response time of few seconds. This paper presents a way to limit measurement time by heuristic knowledge of the properties of the data space and another method based on the concept of Shannon Entropy to find operating parameters satisfying both separation and signal to noise ratio requirements.
KW - Differential mobility spectrometry
KW - DMS
KW - FAIMS
KW - Shannon entropy
U2 - 10.1007/s12127-019-00251-1
DO - 10.1007/s12127-019-00251-1
M3 - Article
JO - International Journal for Ion Mobility Spectrometry
JF - International Journal for Ion Mobility Spectrometry
SN - 1435-6163
ER -