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Processing methods for making porous bioactive glass-based scaffolds-A state-of-the-art review

Research output: Contribution to journalReview ArticleScientificpeer-review

Details

Original languageEnglish
Pages (from-to)1762-1796
Number of pages35
JournalInternational Journal of Applied Ceramic Technology
Volume16
Issue number5
DOIs
Publication statusPublished - Sep 2019
Publication typeA2 Review article in a scientific journal

Abstract

Bioactive glasses exhibit the unique ability of bone bonding, thus creating a stable interface by stimulating bone cells toward mechanisms of regeneration and self-repair activated by ionic dissolution products. Therefore, 3D glass-derived scaffolds can be considered ideal porous templates to be used in bone tissue engineering strategies and regenerative medicine. This review provides a comprehensive overview of all technological aspects relevant to the fabrication of bioactive glass scaffolds, including the fundamentals of materials processing, a summary of the conventional porogen, and template-based methods and of recent additive manufacturing technologies, which are promising for large-scale production of highly reproducible and reliable implants suitable for a wide range of clinical applications.

Keywords

  • additive manufacturing, bioactive glasses, bioceramics, scaffolds, CALCIUM-PHOSPHATE SCAFFOLDS, IN-VITRO CHARACTERIZATION, CERAMIC FOAM SCAFFOLDS, SOL-GEL, MECHANICAL-PROPERTIES, COMPOSITE SCAFFOLDS, BONE SUBSTITUTES, TISSUE, FABRICATION, BIOGLASS(R)

Publication forum classification

Field of science, Statistics Finland