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Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds

Research output: Contribution to journalArticleScientificpeer-review

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Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds. / Baino, Francesco; Barberi, Jacopo; Fiume, Elisa; Orlygsson, Gissur; Massera, Jonathan; Verné, Enrica.

In: Journal of Healthcare Engineering, Vol. 2019, 5153136, 2019.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Baino, F, Barberi, J, Fiume, E, Orlygsson, G, Massera, J & Verné, E 2019, 'Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds', Journal of Healthcare Engineering, vol. 2019, 5153136. https://doi.org/10.1155/2019/5153136

APA

Baino, F., Barberi, J., Fiume, E., Orlygsson, G., Massera, J., & Verné, E. (2019). Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds. Journal of Healthcare Engineering, 2019, [5153136]. https://doi.org/10.1155/2019/5153136

Vancouver

Baino F, Barberi J, Fiume E, Orlygsson G, Massera J, Verné E. Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds. Journal of Healthcare Engineering. 2019;2019. 5153136. https://doi.org/10.1155/2019/5153136

Author

Baino, Francesco ; Barberi, Jacopo ; Fiume, Elisa ; Orlygsson, Gissur ; Massera, Jonathan ; Verné, Enrica. / Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds. In: Journal of Healthcare Engineering. 2019 ; Vol. 2019.

Bibtex - Download

@article{24a76357100341fc894e558198de9923,
title = "Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds",
abstract = "Bioactive silicate glass scaffolds were fabricated by a robocasting process in which all the movements of the printing head were programmed by compiling a script (text file). A printable ink made of glass powder and Pluronic F-127, acting as a binder, was extruded to obtain macroporous scaffolds with a grid-like three-dimensional structure. The scaffold architecture was investigated by scanning electron microscopy and microtomographic analysis, which allowed quantifying the microstructural parameters (pore size 150-180 μm and strut diameter 300 μm). In vitro tests in simulated body fluid (SBF) confirmed the apatite-forming ability (i.e., bioactivity) of the scaffolds. The compressive strength (around 10 MPa for as-produced scaffolds) progressively decreased during immersion in SBF (3.3 MPa after 4 weeks) but remains acceptable for bone repair applications. Taken together, these results (adequate porosity and mechanical strength as well as bioactivity) support the potential suitability of the prepared scaffolds for bone substitution.",
author = "Francesco Baino and Jacopo Barberi and Elisa Fiume and Gissur Orlygsson and Jonathan Massera and Enrica Vern{\'e}",
year = "2019",
doi = "10.1155/2019/5153136",
language = "English",
volume = "2019",
journal = "Journal of Healthcare Engineering",
issn = "2040-2295",
publisher = "Multi-Science Publishing",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Robocasting of Bioactive SiO2-P2O5-CaO-MgO-Na2O-K2O Glass Scaffolds

AU - Baino, Francesco

AU - Barberi, Jacopo

AU - Fiume, Elisa

AU - Orlygsson, Gissur

AU - Massera, Jonathan

AU - Verné, Enrica

PY - 2019

Y1 - 2019

N2 - Bioactive silicate glass scaffolds were fabricated by a robocasting process in which all the movements of the printing head were programmed by compiling a script (text file). A printable ink made of glass powder and Pluronic F-127, acting as a binder, was extruded to obtain macroporous scaffolds with a grid-like three-dimensional structure. The scaffold architecture was investigated by scanning electron microscopy and microtomographic analysis, which allowed quantifying the microstructural parameters (pore size 150-180 μm and strut diameter 300 μm). In vitro tests in simulated body fluid (SBF) confirmed the apatite-forming ability (i.e., bioactivity) of the scaffolds. The compressive strength (around 10 MPa for as-produced scaffolds) progressively decreased during immersion in SBF (3.3 MPa after 4 weeks) but remains acceptable for bone repair applications. Taken together, these results (adequate porosity and mechanical strength as well as bioactivity) support the potential suitability of the prepared scaffolds for bone substitution.

AB - Bioactive silicate glass scaffolds were fabricated by a robocasting process in which all the movements of the printing head were programmed by compiling a script (text file). A printable ink made of glass powder and Pluronic F-127, acting as a binder, was extruded to obtain macroporous scaffolds with a grid-like three-dimensional structure. The scaffold architecture was investigated by scanning electron microscopy and microtomographic analysis, which allowed quantifying the microstructural parameters (pore size 150-180 μm and strut diameter 300 μm). In vitro tests in simulated body fluid (SBF) confirmed the apatite-forming ability (i.e., bioactivity) of the scaffolds. The compressive strength (around 10 MPa for as-produced scaffolds) progressively decreased during immersion in SBF (3.3 MPa after 4 weeks) but remains acceptable for bone repair applications. Taken together, these results (adequate porosity and mechanical strength as well as bioactivity) support the potential suitability of the prepared scaffolds for bone substitution.

U2 - 10.1155/2019/5153136

DO - 10.1155/2019/5153136

M3 - Article

VL - 2019

JO - Journal of Healthcare Engineering

JF - Journal of Healthcare Engineering

SN - 2040-2295

M1 - 5153136

ER -