A Computational Model of Interactions Between Neuronal and Astrocytic Networks: The Role of Astrocytes in the Stability of the Neuronal Firing Rate

Lenk, K., Satuvuori, E., Lallouette, J., Ladrón-de-Guevara, A., Berry, H. & Hyttinen, J. A. K., 22 Jan 2020, In : Frontiers in Computational Neuroscience. 13, 19 p., 92.

Research output: Contribution to journalArticleScientificpeer-review

Unique Features of Network Bursts Emerge From the Complex Interplay of Excitatory and Inhibitory Receptors in Rat Neocortical Networks

Teppola, H., Aćimović, J. & Linne, M. L., 6 Sep 2019, In : FRONTIERS IN CELLULAR NEUROSCIENCE. 13, 377.

Research output: Contribution to journalArticleScientificpeer-review

Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions

Javanainen, M., Enkavi, G., Guixà-Gonzaléz, R., Kulig, W., Martinez-Seara, H., Levental, I. & Vattulainen, I., 1 May 2019, In : PLoS Computational Biology. 15, 5, e1007033.

Research output: Contribution to journalArticleScientificpeer-review

Viability of Mouse Retinal Explant Cultures Assessed by Preservation of Functionality and Morphology

Alarautalahti, V., Ragauskas, S., Hakkarainen, J. J., Uusitalo-Järvinen, H., Uusitalo, H., Hyttinen, J., Kalesnykas, G. & Nymark, S., 1 May 2019, In : Investigative ophthalmology & visual science. 60, 6, p. 1914-1927 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Advances in Human Stem Cell-Derived Neuronal Cell Culturing and Analysis

Ylä-Outinen, L., Tanskanen, J. M. A., Kapucu, F. E., Hyysalo, A., Hyttinen, J. A. K. & Narkilahti, S., 2019, In Vitro Neuronal Networks: From Culturing Methods to Neuro-Technological Applications. Springer New York LLC, p. 299-329 31 p. (Advances in Neurobiology; vol. 22).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Astrocyte lineage cells are essential for functional neuronal differentiation and synapse maturation in human iPSC-derived neural networks

Klapper, S. D., Garg, P., Dagar, S., Lenk, K., Gottmann, K. & Nieweg, K., 2019, In : Glia. 67, 10, p. 1893-1909 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Data-driven study of synchronous popula on ac vity in generic spiking neuronal networks: How much do we capture using the minimal model for the considered phenomena?

Acimovic, J., Teppola, H., Mäki-Marttunen, T. M. & Linne, M-L., 20 Sep 2018.

Research output: Other conference contributionPaper, poster or abstractScientific

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling

Pantsar, T., Rissanen, S., Dauch, D., Laitinen, T., Vattulainen, I. & Poso, A., 10 Sep 2018, In : PLoS Computational Biology. 14, 9, e1006458.

Research output: Contribution to journalArticleScientificpeer-review

Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin

Enkavi, G., Mikkolainen, H., Güngör, B., Ikonen, E. & Vattulainen, I., 1 Oct 2017, In : PLoS Computational Biology. 13, 10, e1005831.

Research output: Contribution to journalArticleScientificpeer-review

Atomistic fingerprint of hyaluronan–CD44 binding

Vuorio, J., Vattulainen, I. & Martinez-Seara, H., 1 Jul 2017, In : PLoS Computational Biology. 13, 7, e1005663.

Research output: Contribution to journalArticleScientificpeer-review

Network-wide adaptive burst detection depicts neuronal activity with improved accuracy

Välkki, I. A., Lenk, K., Mikkonen, J. E., Kapucu, F. E. & Hyttinen, J. A. K., 31 May 2017, In : Frontiers in Computational Neuroscience. 11, 40.

Research output: Contribution to journalArticleScientificpeer-review

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol

Teppola, H., Sarkanen, J. R., Jalonen, T. O. & Linne, M-L., 2016, In : Neurochemical Research. 41, 4, p. 731-747

Research output: Contribution to journalArticleScientificpeer-review

The effects of neuron morphology on graph theoretic measures of network connectivity: The analysis of a two-level statistical model

Acimovic, J., Mäki-Marttunen, T. & Linne, M-L., 10 Jun 2015, In : Frontiers in Neuroanatomy. 9, June, 76.

Research output: Contribution to journalArticleScientificpeer-review

Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway

Saurus, P., Kuusela, S., Lehtonen, E., Hyvönen, M. E., Ristola, M., Fogarty, C. L., Tienari, J., Lassenius, M. I., Forsblom, C., Lehto, M., Saleem, M. A., Groop, P. H., Holthöfer, H. & Lehtonen, S., 1 May 2015, In : CELL DEATH AND DISEASE. 6, 5, e1752.

Research output: Contribution to journalArticleScientificpeer-review

Effects of cytokine activation and oxidative stress on the function of the human embryonic stem cell–derived retinal pigment epithelial cells

Juuti-Uusitalo, K., Nieminen, M., Treumer, F., Ampuja, M., Kallioniemi, A., Klettner, A. & Skottman, H., 2015, In : Investigative Ophthalmology and Visual Science. 56, 11, p. 6265-6274 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Patient-specific induced pluripotent stem cell—derived RPE cells: Understanding the pathogenesis of retinopathy in long-chain 3-hydroxyacyl-CoA dehydrogenase deiciency

Polinati, P. P., Ilmarinen, T., Trokovic, R., Hyotylainen, T., Otonkoski, T., Suomalainen, A., Skottman, H. & Tynitiina, T., 2015, In : Investigative Ophthalmology and Visual Science. 56, 5, p. 3371-3382 12 p.

Research output: Contribution to journalArticleScientificpeer-review

In silico study on structure and dynamics in bursting neuronal networks

Mäki-Marttunen, T. M., Acimovic, J., Ruohonen, K. P. & Linne, M-L., 13 Oct 2012, Neuroscience 2012; 42nd Annual Meeting, New Orleans, USA, October 14-18, 2012. Society for Neuroscience (SfN), 1 p. 300.26/DDD70

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Significance of graph theoretic measures in predicting neuronal network activity

Mäki-Marttunen, T. M., Acimovic, J., Ruohonen, K. P. & Linne, M-L., 23 Feb 2012, Proceedings of The 9th annual Computational and Systems Neuroscience meeting (COSYNE 2012). Salt Lake City, p. 55-55 1 p. I-15

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition

Dixit, D., Sharma, V., Ghosh, S., Mehta, V. S. & Sen, E., Feb 2012, In : CELL DEATH AND DISEASE. 3, 2, e271.

Research output: Contribution to journalArticleScientificpeer-review

Cortical spreading depression in alpha-synuclein knockout mice

Pelkonen, A. & Yavich, L., Jan 2012, In : SYNAPSE. 66, 1, p. 81-84 4 p.

Research output: Contribution to journalArticleScientificpeer-review

COX-2 regulates the proliferation of glioma stem like cells

Sharma, V., Dixit, D., Ghosh, S. & Sen, E., Oct 2011, In : NEUROCHEMISTRY INTERNATIONAL. 59, 5, p. 567-571 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Effects of local structure of neuronal networks on spiking activity in silico

Mäki-Marttunen, T. M., Acimovic, J., Ruohonen, K. P. & Linne, M-L., 18 Jul 2011, Twentieth Annual Computational Neuroscience Meeting: CNS*2011. Fellous, J-M. & Prinz, A. (eds.). Stockholm: BioMed Central, Vol. 12 (Suppl 1). p. P202 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Emergence of global and local structural features during development of neuronal networks

Acimovic, J., 6 Jun 2011, Proceedings of the Eighth International Workshop on Computational Systems Biology, WCSB 2011, June 6-8, 2011, Zürich, Switzerland . Tampere: TICSP, (TICSP Series ; vol. 57).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Pathway analysis of expression data: Deciphering functional building blocks of complex diseases

Emmert-Streib, F. & Glazko, G. V., May 2011, In : PLoS Computational Biology. 7, 5, e1002053.

Research output: Contribution to journalArticleScientificpeer-review

Effects of structure on spontaneous activity in simulated neuronal networks

Mäki-Marttunen, T., Acimovic, J., Ruohonen, K. & Linne, M-L., 11 Apr 2011, Proceedings of Mathematical Neuroscience (ICMS 2011), April 11-13, 2011, Edinburgh, Scotland.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Neural networks, cell cultures and some older work on data analysis.

Acimovic, J., 15 Jun 2009.

Research output: Other conference contributionPaper, poster or abstractScientific

Influence of the neural network topology on the learning dynamics

Emmert-Streib, F., May 2006, In : Neurocomputing. 69, 10-12, p. 1179-1182 4 p.

Research output: Contribution to journalArticleScientificpeer-review

A constrained HMM-based approach to the estimation of perceptual switching dynamics in pigeons

Otterpohl, J. R., Emmert-Streib, F. & Pawelzik, K., Jun 2001, In : Neurocomputing. 38-40, p. 1495-1501 7 p.

Research output: Contribution to journalArticleScientificpeer-review