A Computational Model of Interactions Between Neuronal and Astrocytic Networks : The Role of Astrocytes in the Stability of the Neuronal Firing Rate. / Lenk, Kerstin; Satuvuori, Eero; Lallouette, Jules; Ladrón-de-Guevara, Antonio; Berry, Hugues; Hyttinen, Jari A. K.

In: Frontiers in Computational Neuroscience, Vol. 13, 92, 22.01.2020.

Research output: Contribution to journalArticleScientificpeer-review

Unique Features of Network Bursts Emerge From the Complex Interplay of Excitatory and Inhibitory Receptors in Rat Neocortical Networks. / Teppola, Heidi; Aćimović, Jugoslava; Linne, Marja Leena.

In: FRONTIERS IN CELLULAR NEUROSCIENCE, Vol. 13, 377, 06.09.2019.

Research output: Contribution to journalArticleScientificpeer-review

Reduced level of docosahexaenoic acid shifts GPCR neuroreceptors to less ordered membrane regions. / Javanainen, Matti; Enkavi, Giray; Guixà-Gonzaléz, Ramon; Kulig, Waldemar; Martinez-Seara, Hector; Levental, Ilya; Vattulainen, Ilpo.

In: PLoS Computational Biology, Vol. 15, No. 5, e1007033, 01.05.2019.

Research output: Contribution to journalArticleScientificpeer-review

Viability of Mouse Retinal Explant Cultures Assessed by Preservation of Functionality and Morphology. / Alarautalahti, Virpi; Ragauskas, Symantas; Hakkarainen, Jenni J.; Uusitalo-Järvinen, Hannele; Uusitalo, Hannu; Hyttinen, Jari; Kalesnykas, Giedrius; Nymark, Soile.

In: Investigative ophthalmology & visual science, Vol. 60, No. 6, 01.05.2019, p. 1914-1927.

Research output: Contribution to journalArticleScientificpeer-review

Advances in Human Stem Cell-Derived Neuronal Cell Culturing and Analysis. / Ylä-Outinen, Laura; Tanskanen, Jarno M.A.; Kapucu, Fikret E.; Hyysalo, Anu; Hyttinen, Jari A.K.; Narkilahti, Susanna.

In Vitro Neuronal Networks: From Culturing Methods to Neuro-Technological Applications. Springer New York LLC, 2019. p. 299-329 (Advances in Neurobiology; Vol. 22).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Astrocyte lineage cells are essential for functional neuronal differentiation and synapse maturation in human iPSC-derived neural networks. / Klapper, Simon D.; Garg, Pretty; Dagar, Sushma; Lenk, Kerstin; Gottmann, Kurt; Nieweg, Katja.

In: Glia, Vol. 67, No. 10, 2019, p. 1893-1909.

Research output: Contribution to journalArticleScientificpeer-review

Data-driven study of synchronous popula on ac vity in generic spiking neuronal networks: How much do we capture using the minimal model for the considered phenomena? / Acimovic, Jugoslava; Teppola, Heidi; Mäki-Marttunen, Tuomo Mikael; Linne, Marja-Leena.

2018. Paper presented at Brain and Mind Symposium 2018, Helsinki, Finland.

Research output: Other conference contributionPaper, poster or abstractScientific

Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling. / Pantsar, Tatu; Rissanen, Sami; Dauch, Daniel; Laitinen, Tuomo; Vattulainen, Ilpo; Poso, Antti.

In: PLoS Computational Biology, Vol. 14, No. 9, e1006458, 10.09.2018.

Research output: Contribution to journalArticleScientificpeer-review

Concerted regulation of npc2 binding to endosomal/lysosomal membranes by bis(monoacylglycero)phosphate and sphingomyelin. / Enkavi, Giray; Mikkolainen, Heikki; Güngör, Burçin; Ikonen, Elina; Vattulainen, Ilpo.

In: PLoS Computational Biology, Vol. 13, No. 10, e1005831, 01.10.2017.

Research output: Contribution to journalArticleScientificpeer-review

Atomistic fingerprint of hyaluronan–CD44 binding. / Vuorio, Joni; Vattulainen, Ilpo; Martinez-Seara, Hector.

In: PLoS Computational Biology, Vol. 13, No. 7, e1005663, 01.07.2017.

Research output: Contribution to journalArticleScientificpeer-review

Network-wide adaptive burst detection depicts neuronal activity with improved accuracy. / Välkki, Inkeri A.; Lenk, Kerstin; Mikkonen, Jarno E.; Kapucu, Fikret E.; Hyttinen, Jari A.K.

In: Frontiers in Computational Neuroscience, Vol. 11, 40, 31.05.2017.

Research output: Contribution to journalArticleScientificpeer-review

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol. / Teppola, Heidi; Sarkanen, Jertta Riina; Jalonen, Tuula O.; Linne, Marja-Leena.

In: Neurochemical Research, Vol. 41, No. 4, 2016, p. 731-747.

Research output: Contribution to journalArticleScientificpeer-review

The effects of neuron morphology on graph theoretic measures of network connectivity : The analysis of a two-level statistical model. / Acimovic, Jugoslava; Mäki-Marttunen, Tuomo; Linne, Marja-Leena.

In: Frontiers in Neuroanatomy, Vol. 9, No. June, 76, 10.06.2015.

Research output: Contribution to journalArticleScientificpeer-review

Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway. / Saurus, P.; Kuusela, S.; Lehtonen, E.; Hyvönen, M. E.; Ristola, M.; Fogarty, C. L.; Tienari, J.; Lassenius, M. I.; Forsblom, C.; Lehto, M.; Saleem, M. A.; Groop, P. H.; Holthöfer, H.; Lehtonen, S.

In: CELL DEATH AND DISEASE, Vol. 6, No. 5, e1752, 01.05.2015.

Research output: Contribution to journalArticleScientificpeer-review

Effects of cytokine activation and oxidative stress on the function of the human embryonic stem cell–derived retinal pigment epithelial cells. / Juuti-Uusitalo, Kati; Nieminen, Monica; Treumer, Felix; Ampuja, Minna; Kallioniemi, Anne; Klettner, Alexa; Skottman, Heli.

In: Investigative Ophthalmology and Visual Science, Vol. 56, No. 11, 2015, p. 6265-6274.

Research output: Contribution to journalArticleScientificpeer-review

Patient-specific induced pluripotent stem cell—derived RPE cells : Understanding the pathogenesis of retinopathy in long-chain 3-hydroxyacyl-CoA dehydrogenase deiciency. / Polinati, Padmini P.; Ilmarinen, Tanja; Trokovic, Ras; Hyotylainen, Tuulia; Otonkoski, Timo; Suomalainen, Anu; Skottman, Heli; Tynitiina, Tiina.

In: Investigative Ophthalmology and Visual Science, Vol. 56, No. 5, 2015, p. 3371-3382.

Research output: Contribution to journalArticleScientificpeer-review

In silico study on structure and dynamics in bursting neuronal networks. / Mäki-Marttunen, Tuomo Mikael; Acimovic, Jugoslava; Ruohonen, Keijo Pellervo; Linne, Marja-Leena.

Neuroscience 2012; 42nd Annual Meeting, New Orleans, USA, October 14-18, 2012. Society for Neuroscience (SfN), 2012. 300.26/DDD70.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Significance of graph theoretic measures in predicting neuronal network activity. / Mäki-Marttunen, Tuomo Mikael; Acimovic, Jugoslava; Ruohonen, Keijo Pellervo; Linne, Marja-Leena.

Proceedings of The 9th annual Computational and Systems Neuroscience meeting (COSYNE 2012). Salt Lake City, 2012. p. 55-55 I-15.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition. / Dixit, D.; Sharma, V.; Ghosh, S.; Mehta, V. S.; Sen, E.

In: CELL DEATH AND DISEASE, Vol. 3, No. 2, e271, 02.2012.

Research output: Contribution to journalArticleScientificpeer-review

Cortical spreading depression in alpha-synuclein knockout mice. / Pelkonen, Anssi; Yavich, Leonid.

In: SYNAPSE, Vol. 66, No. 1, 01.2012, p. 81-84.

Research output: Contribution to journalArticleScientificpeer-review

COX-2 regulates the proliferation of glioma stem like cells. / Sharma, Vivek; Dixit, Deobrat; Ghosh, Sadashib; Sen, Ellora.

In: NEUROCHEMISTRY INTERNATIONAL, Vol. 59, No. 5, 10.2011, p. 567-571.

Research output: Contribution to journalArticleScientificpeer-review

Effects of local structure of neuronal networks on spiking activity in silico. / Mäki-Marttunen, Tuomo Mikael; Acimovic, Jugoslava; Ruohonen, Keijo Pellervo; Linne, Marja-Leena.

Twentieth Annual Computational Neuroscience Meeting: CNS*2011. ed. / Jean-Marc Fellous; Astrid Prinz. Vol. 12 (Suppl 1) Stockholm : BioMed Central, 2011. p. P202.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Emergence of global and local structural features during development of neuronal networks. / Acimovic, Jugoslava.

Proceedings of the Eighth International Workshop on Computational Systems Biology, WCSB 2011, June 6-8, 2011, Zürich, Switzerland . Tampere : TICSP, 2011. (TICSP Series ; Vol. 57).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Pathway analysis of expression data : Deciphering functional building blocks of complex diseases. / Emmert-Streib, Frank; Glazko, Galina V.

In: PLoS Computational Biology, Vol. 7, No. 5, e1002053, 05.2011.

Research output: Contribution to journalArticleScientificpeer-review

Effects of structure on spontaneous activity in simulated neuronal networks. / Mäki-Marttunen, Tuomo; Acimovic, Jugoslava; Ruohonen, Keijo; Linne, Marja-Leena.

Proceedings of Mathematical Neuroscience (ICMS 2011), April 11-13, 2011, Edinburgh, Scotland. 2011.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Neural networks, cell cultures and some older work on data analysis. / Acimovic, Jugoslava.

2009. Paper presented at Okinawa Computational Neuroscience Course 2009, Japan.

Research output: Other conference contributionPaper, poster or abstractScientific

Influence of the neural network topology on the learning dynamics. / Emmert-Streib, Frank.

In: Neurocomputing, Vol. 69, No. 10-12, 05.2006, p. 1179-1182.

Research output: Contribution to journalArticleScientificpeer-review

A constrained HMM-based approach to the estimation of perceptual switching dynamics in pigeons. / Otterpohl, J. R.; Emmert-Streib, F.; Pawelzik, K.

In: Neurocomputing, Vol. 38-40, 06.2001, p. 1495-1501.

Research output: Contribution to journalArticleScientificpeer-review