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Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

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Details

Original languageEnglish
Pages (from-to)8466-8471
Number of pages6
JournalNanoscale
Volume5
Issue number18
DOIs
Publication statusPublished - 21 Sep 2013
Publication typeA1 Journal article-refereed

Abstract

We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

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Field of science, Statistics Finland