Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons
Research output: Contribution to journal › Article › Scientific › peer-review
|Number of pages||6|
|Publication status||Published - 21 Sep 2013|
|Publication type||A1 Journal article-refereed|
We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.