Tampere University of Technology

TUTCRIS Research Portal

Single KTP nanocrystals as second-harmonic generation biolabels in cortical neurons

Research output: Contribution to journalArticleScientificpeer-review


Original languageEnglish
Pages (from-to)8466-8471
Number of pages6
Issue number18
Publication statusPublished - 21 Sep 2013
Publication typeA1 Journal article-refereed


We report an efficient colloidal synthesis of KTiOPO4 (KTP) nanocrystals with excellent crystallinity and the direct observation of optical second-harmonic generation (SHG) from discrete KTP nanocrystals in neurons cultured from mammalian brain cortex. Direct internalization and monitoring of these nanoparticles was successfully achieved without limitations from cytotoxicity, bleaching and blinking emission.

ASJC Scopus subject areas

Publication forum classification

Field of science, Statistics Finland