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Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering

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Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering. / Tainio, J. M.; Salazar, D. A.Avila; Nommeots-Nomm, A.; Roiland, C.; Bureau, B.; Neuville, D. R.; Brauer, D. S.; Massera, J.

In: Journal of Non-Crystalline Solids, Vol. 533, 119893, 01.04.2020.

Research output: Contribution to journalArticleScientificpeer-review

Harvard

Tainio, JM, Salazar, DAA, Nommeots-Nomm, A, Roiland, C, Bureau, B, Neuville, DR, Brauer, DS & Massera, J 2020, 'Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering', Journal of Non-Crystalline Solids, vol. 533, 119893. https://doi.org/10.1016/j.jnoncrysol.2020.119893

APA

Tainio, J. M., Salazar, D. A. A., Nommeots-Nomm, A., Roiland, C., Bureau, B., Neuville, D. R., ... Massera, J. (2020). Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering. Journal of Non-Crystalline Solids, 533, [119893]. https://doi.org/10.1016/j.jnoncrysol.2020.119893

Vancouver

Tainio JM, Salazar DAA, Nommeots-Nomm A, Roiland C, Bureau B, Neuville DR et al. Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering. Journal of Non-Crystalline Solids. 2020 Apr 1;533. 119893. https://doi.org/10.1016/j.jnoncrysol.2020.119893

Author

Tainio, J. M. ; Salazar, D. A.Avila ; Nommeots-Nomm, A. ; Roiland, C. ; Bureau, B. ; Neuville, D. R. ; Brauer, D. S. ; Massera, J. / Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering. In: Journal of Non-Crystalline Solids. 2020 ; Vol. 533.

Bibtex - Download

@article{9202281a6f8c40b3a39ca4c6c1f84372,
title = "Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering",
abstract = "Borosilicate bioactive glasses are promising for bone tissue engineering. The objective was to assess the impact of magnesium and/or strontium, when substituted for calcium on the glasses' thermal and dissolution properties. Both Mg and Sr substitution appeared to enhance the hot forming domain, i.e. the ability to hot process (sinter, draw fibres) without adverse crystallization. Structural analysis indicated that substitution of MgO and/or SrO for CaO results in changes in the BO3/BO4 ratio as well as in the ratio between bridging and non-bridging oxygen atoms in the silicate structure. Additionally, a de-shielding effect was noticed when Ca, Mg and Sr are present together in the glass network, possibly owing to PO4 3− charge-balanced preferentially by Na+. The Mg and/or Sr substitution resulted in a lower ion release in simulated body fluid and delayed formation of hydroxyapatite. However, once this layer formed it consisted of a Mg/Sr-substituted apatite. This work highlights the effect of combined ionic substitutions on bioactive glass structure and properties.",
keywords = "Bioactive glasses, Borosilicate glasses, In vitro dissolution, Structural properties, Tissue engineering",
author = "Tainio, {J. M.} and Salazar, {D. A.Avila} and A. Nommeots-Nomm and C. Roiland and B. Bureau and Neuville, {D. R.} and Brauer, {D. S.} and J. Massera",
year = "2020",
month = "4",
day = "1",
doi = "10.1016/j.jnoncrysol.2020.119893",
language = "English",
volume = "533",
journal = "Journal of Non-Crystalline Solids",
issn = "0022-3093",
publisher = "Elsevier",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Structure and in vitro dissolution of Mg and Sr containing borosilicate bioactive glasses for bone tissue engineering

AU - Tainio, J. M.

AU - Salazar, D. A.Avila

AU - Nommeots-Nomm, A.

AU - Roiland, C.

AU - Bureau, B.

AU - Neuville, D. R.

AU - Brauer, D. S.

AU - Massera, J.

PY - 2020/4/1

Y1 - 2020/4/1

N2 - Borosilicate bioactive glasses are promising for bone tissue engineering. The objective was to assess the impact of magnesium and/or strontium, when substituted for calcium on the glasses' thermal and dissolution properties. Both Mg and Sr substitution appeared to enhance the hot forming domain, i.e. the ability to hot process (sinter, draw fibres) without adverse crystallization. Structural analysis indicated that substitution of MgO and/or SrO for CaO results in changes in the BO3/BO4 ratio as well as in the ratio between bridging and non-bridging oxygen atoms in the silicate structure. Additionally, a de-shielding effect was noticed when Ca, Mg and Sr are present together in the glass network, possibly owing to PO4 3− charge-balanced preferentially by Na+. The Mg and/or Sr substitution resulted in a lower ion release in simulated body fluid and delayed formation of hydroxyapatite. However, once this layer formed it consisted of a Mg/Sr-substituted apatite. This work highlights the effect of combined ionic substitutions on bioactive glass structure and properties.

AB - Borosilicate bioactive glasses are promising for bone tissue engineering. The objective was to assess the impact of magnesium and/or strontium, when substituted for calcium on the glasses' thermal and dissolution properties. Both Mg and Sr substitution appeared to enhance the hot forming domain, i.e. the ability to hot process (sinter, draw fibres) without adverse crystallization. Structural analysis indicated that substitution of MgO and/or SrO for CaO results in changes in the BO3/BO4 ratio as well as in the ratio between bridging and non-bridging oxygen atoms in the silicate structure. Additionally, a de-shielding effect was noticed when Ca, Mg and Sr are present together in the glass network, possibly owing to PO4 3− charge-balanced preferentially by Na+. The Mg and/or Sr substitution resulted in a lower ion release in simulated body fluid and delayed formation of hydroxyapatite. However, once this layer formed it consisted of a Mg/Sr-substituted apatite. This work highlights the effect of combined ionic substitutions on bioactive glass structure and properties.

KW - Bioactive glasses

KW - Borosilicate glasses

KW - In vitro dissolution

KW - Structural properties

KW - Tissue engineering

U2 - 10.1016/j.jnoncrysol.2020.119893

DO - 10.1016/j.jnoncrysol.2020.119893

M3 - Article

VL - 533

JO - Journal of Non-Crystalline Solids

JF - Journal of Non-Crystalline Solids

SN - 0022-3093

M1 - 119893

ER -