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Synthesis of chlorinated 5-hydroxy 4-methyl-2(5H)-furanones and mucochloric acid

Research output: Contribution to journalArticleScientificpeer-review


Original languageEnglish
Pages (from-to)3905-3908
Number of pages4
JournalTetrahedron Letters
Issue number22
Publication statusPublished - 29 May 1995
Externally publishedYes
Publication typeA1 Journal article-refereed


An improved procedure for the synthesis of chlorinated 5-hydroxy-4-methyl-2(5H)-furanones is described. By this method also carbon-labelled (13C and 14C at C-3) hydroxyfuranones, including mucochioric acid, can be prepared. Each step of the method was examined in an effort to optimize both the yield and the purity of the compounds.