Tampere University of Technology

TUTCRIS Research Portal

The Experience of Treating Drooling with Repeated Botulinum Toxin Injections

Research output: Contribution to journalArticleScientificpeer-review

Details

Original languageEnglish
Pages (from-to)333-338
Number of pages6
JournalORL: JOURNAL FOR OTO: RHINO: LARYNGOLOGY AND ITS RELATED SPECIALTIES
Volume77
Issue number6
DOIs
Publication statusPublished - 1 Nov 2015
Publication typeA1 Journal article-refereed

Abstract

Botulinum toxin A (BTX-A) injections to the salivary glands are effective in the treatment of drooling, and complications are rare. However, there are only a few previous reports on the long-term use of BTX-A injections. This study retrospectively analyzes our experience of treating drooling with repeated BTX-A injections in patients with neurodegenerative diseases. All patients who received repeated BTX-A injections to the submandibular glands at Tampere University Hospital in 2004-2013 were included in the analysis. Six patients, aged from 6 to 21 years, were included in the study, and a total of 41 bilateral BTX-A injections were administered to their submandibular glands. The average number of injections per patient was 6 (range: 3-11). The average interval between the injections was 9.8 months (range: 4-18), and 95% (39/41) of the injections were performed with good response. The complication rate of the BTX-A injections was 2.4% (1/41), since one of the patients had swallowing problems after an injection. BTX-A injections to the submandibular glands are effective and have a low morbidity rate, and repeated injections can be recommended as long-term treatment of drooling.

ASJC Scopus subject areas

Keywords

  • Adverse effect, Botulinum toxin, Drooling, Salivary gland, Sialorrhea