TUTCRIS - Tampereen teknillinen yliopisto

TUTCRIS

Tutkimusryhmä: Molecular Signaling Lab

Tutkimusyksikkö: Tutkimusryhmä

Yksikön kuvaus

Molecular signaling network plays the crucial role in gene expression regulation and cell fate determination. We investigate the molecular signaling pathways of cancer and other diseases. Improper intra and/or extracellular signal transduction affects cells well-being and lead to various diseases. Specifically, we study the canonical and non-canonical signaling pathways activated by membrane receptor at single cell level. For this, our group deploys interdisciplinary research knowledge such as Biosensor and biomeasurements, Pharmaceutical sciences, Single cell imaging, Molecular signal processing, Computational models and bioinformatics. The group develops and apply synthetic signaling compounds, biosensor, modeling, and simulation health and disease. We are the part of Computational Systems Biology Group, The Faculty of Biomedical Sciences and Engineering at BioMediTech–Tampere University of Technology.

Uusimmat julkaisut

  1. Julkaistu

    Base catalysed N-functionalisation of boroxazolidones

    J., R., Mannoja, J., Nguyen, T., N., A., N. M., K., Franzén, R. G., Kandhavelu, M. & Candeias, N. R., 2017, julkaisussa : RSC Advances. 7, 33, s. 20620-20627 8 Sivumäärä

    Tutkimustuotosvertaisarvioitu

  2. Julkaistu

    Synthesis of phenol-derivatives and biological screening for anticancer activity

    Karjalainen, A., Doan, P., Sandberg, O., Chandraseelan, J. G., Yli-Harja, O., R. Candeias, N. & Kandhavelu, M., 2017, julkaisussa : Anti-Cancer Agents in Medicinal Chemistry. 17, 12, s. 1710-1720

    Tutkimustuotosvertaisarvioitu

  3. Julkaistu

    Real-time observation of bacterial gene expression noise

    Anufrieva, O., Sala, A., Yli-Harja, O. & Kandhavelu, M., kesäkuuta 2016, julkaisussa : Nano Communication Networks. 8, s. 68-75

    Tutkimustuotosvertaisarvioitu

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