Direct Measurement of Contraction Force in Human Cardiac Tissue Model Using Piezoelectric Cantilever Sensor Technique
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Yksityiskohdat
| Alkuperäiskieli | Englanti |
|---|---|
| Sivut | 155-160 |
| Sivumäärä | 6 |
| Julkaisu | Current Applied Physics |
| Vuosikerta | 20 |
| Numero | 1 |
| DOI - pysyväislinkit | |
| Tila | Hyväksytty/In press - 25 lokakuuta 2019 |
| OKM-julkaisutyyppi | A1 Alkuperäisartikkeli |
Tiivistelmä
A proof-of-concept method for measuring cardiac tissue contraction force using an in-house-developed piezoelectric cantilever sensor system is demonstrated. Contracting forces of 7.2 to 16.6 μN were measured from a human cardiac tissue construct. Beating cardiac tissue constructs were monitored in-situ under a microscope during the contraction force measurements. Development of the measurement method allows very low forces such as the ones that appear in biological small scale systems to be determined.