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Direct Measurement of Contraction Force in Human Cardiac Tissue Model Using Piezoelectric Cantilever Sensor Technique

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Yksityiskohdat

AlkuperäiskieliEnglanti
Sivut155-160
Sivumäärä6
JulkaisuCurrent Applied Physics
Vuosikerta20
Numero1
DOI - pysyväislinkit
TilaHyväksytty/In press - 25 lokakuuta 2019
OKM-julkaisutyyppiA1 Alkuperäisartikkeli

Tiivistelmä

A proof-of-concept method for measuring cardiac tissue contraction force using an in-house-developed piezoelectric cantilever sensor system is demonstrated. Contracting forces of 7.2 to 16.6 μN were measured from a human cardiac tissue construct. Beating cardiac tissue constructs were monitored in-situ under a microscope during the contraction force measurements. Development of the measurement method allows very low forces such as the ones that appear in biological small scale systems to be determined.

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