TUTCRIS - Tampereen teknillinen yliopisto

TUTCRIS

Global information processing in gene networks: Fault tolerance

Tutkimustuotosvertaisarvioitu

Yksityiskohdat

AlkuperäiskieliEnglanti
OtsikkoProceedings of the Bio-Inspired Models of Network, Information, and Computing Systems, Bionetics 2007
Sivut326-329
Sivumäärä4
DOI - pysyväislinkit
TilaJulkaistu - 2007
Julkaistu ulkoisestiKyllä
OKM-julkaisutyyppiA4 Artikkeli konferenssijulkaisussa
Tapahtuma2nd International Conference on Bio-Inspired Models of Network, Information, and Computing Systems, BIONETICS 2007 - Budapest, Unkari
Kesto: 10 joulukuuta 200712 joulukuuta 2007

Conference

Conference2nd International Conference on Bio-Inspired Models of Network, Information, and Computing Systems, BIONETICS 2007
MaaUnkari
KaupunkiBudapest
Ajanjakso10/12/0712/12/07

Tiivistelmä

In this paper we study the fault tolerance of gene networks. We assume single gene knockouts and investigate the effect this kind of perturbation has on the communication between genes globally. For our study we use directed scale-free networks resembling gene networks, e.g., signaling or proteinprotein interaction networks, and define a Markov process based on the network topology to model communication. This allows us to evaluate the spread of information in the network and, hence, detect differences due to single gene knockouts in the gene-gene communication asymptotically.