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TUTCRIS

Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate

Tutkimustuotosvertaisarvioitu

Standard

Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate. / Ahola, Niina; Veiranto, Minna; Rich, Jaana; Efimov, Alexander; Hannula, Markus; Seppälä, Jukka; Kellomäki, Minna.

julkaisussa: Journal of Biomaterials Applications, Vuosikerta 28, Nro 4, 2013, s. 529-543.

Tutkimustuotosvertaisarvioitu

Harvard

Ahola, N, Veiranto, M, Rich, J, Efimov, A, Hannula, M, Seppälä, J & Kellomäki, M 2013, 'Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate', Journal of Biomaterials Applications, Vuosikerta. 28, Nro 4, Sivut 529-543. https://doi.org/10.1177/0885328212462258

APA

Ahola, N., Veiranto, M., Rich, J., Efimov, A., Hannula, M., Seppälä, J., & Kellomäki, M. (2013). Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate. Journal of Biomaterials Applications, 28(4), 529-543. https://doi.org/10.1177/0885328212462258

Vancouver

Ahola N, Veiranto M, Rich J, Efimov A, Hannula M, Seppälä J et al. Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate. Journal of Biomaterials Applications. 2013;28(4):529-543. https://doi.org/10.1177/0885328212462258

Author

Ahola, Niina ; Veiranto, Minna ; Rich, Jaana ; Efimov, Alexander ; Hannula, Markus ; Seppälä, Jukka ; Kellomäki, Minna. / Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate. Julkaisussa: Journal of Biomaterials Applications. 2013 ; Vuosikerta 28, Nro 4. Sivut 529-543.

Bibtex - Lataa

@article{cbf5519e65d24557940d16ac78199a3e,
title = "Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate",
abstract = "There is an increasing need for synthetic bone substitute materials that decrease the need for allografts and autografts. In this study, composites of β-TCP and a biodegradable poly(L-lactide-co-ε-caprolactone) were manufactured using extrusion to form biodegradable composites with high β-TCP contents for osteoconductivity. The hydrolytic degradation of the composites containing 0, 10, 20, 35 and 50{\%} of β-TCP was studied in vitro for 52 weeks. During the study, it was observed that β-TCP did not have an effect on the degradation rate of the polymer matrix. However, the crystallinity of the materials increased throughout the test series and changes in Tgs were also observed as the comonomer ratio of the polymer matrix changed as the degradation proceeded. The results show that the materials have desirable degradation properties and, thus, possess great potential as bioabsorbable and osteoconductive bone filling materials.",
author = "Niina Ahola and Minna Veiranto and Jaana Rich and Alexander Efimov and Markus Hannula and Jukka Sepp{\"a}l{\"a} and Minna Kellom{\"a}ki",
note = "Online First : Published online before print October 9, 2012, doi: 10.1177/0885328212462258 : J Biomater Appl October 9, 2012 0885328212462258<br/>Contribution: organisation=bme,FACT1=0.5<br/>Contribution: organisation=keb kem,FACT2=0.5<br/>Publisher name: Sage",
year = "2013",
doi = "10.1177/0885328212462258",
language = "English",
volume = "28",
pages = "529--543",
journal = "Journal of Biomaterials Applications",
issn = "0885-3282",
publisher = "SAGE Publications",
number = "4",

}

RIS (suitable for import to EndNote) - Lataa

TY - JOUR

T1 - Hydrolytic degradation of composites of poly(L-lactide-co-epsilon-caprolactone) 70/30 and beta-tricalcium phosphate

AU - Ahola, Niina

AU - Veiranto, Minna

AU - Rich, Jaana

AU - Efimov, Alexander

AU - Hannula, Markus

AU - Seppälä, Jukka

AU - Kellomäki, Minna

N1 - Online First : Published online before print October 9, 2012, doi: 10.1177/0885328212462258 : J Biomater Appl October 9, 2012 0885328212462258<br/>Contribution: organisation=bme,FACT1=0.5<br/>Contribution: organisation=keb kem,FACT2=0.5<br/>Publisher name: Sage

PY - 2013

Y1 - 2013

N2 - There is an increasing need for synthetic bone substitute materials that decrease the need for allografts and autografts. In this study, composites of β-TCP and a biodegradable poly(L-lactide-co-ε-caprolactone) were manufactured using extrusion to form biodegradable composites with high β-TCP contents for osteoconductivity. The hydrolytic degradation of the composites containing 0, 10, 20, 35 and 50% of β-TCP was studied in vitro for 52 weeks. During the study, it was observed that β-TCP did not have an effect on the degradation rate of the polymer matrix. However, the crystallinity of the materials increased throughout the test series and changes in Tgs were also observed as the comonomer ratio of the polymer matrix changed as the degradation proceeded. The results show that the materials have desirable degradation properties and, thus, possess great potential as bioabsorbable and osteoconductive bone filling materials.

AB - There is an increasing need for synthetic bone substitute materials that decrease the need for allografts and autografts. In this study, composites of β-TCP and a biodegradable poly(L-lactide-co-ε-caprolactone) were manufactured using extrusion to form biodegradable composites with high β-TCP contents for osteoconductivity. The hydrolytic degradation of the composites containing 0, 10, 20, 35 and 50% of β-TCP was studied in vitro for 52 weeks. During the study, it was observed that β-TCP did not have an effect on the degradation rate of the polymer matrix. However, the crystallinity of the materials increased throughout the test series and changes in Tgs were also observed as the comonomer ratio of the polymer matrix changed as the degradation proceeded. The results show that the materials have desirable degradation properties and, thus, possess great potential as bioabsorbable and osteoconductive bone filling materials.

U2 - 10.1177/0885328212462258

DO - 10.1177/0885328212462258

M3 - Article

VL - 28

SP - 529

EP - 543

JO - Journal of Biomaterials Applications

JF - Journal of Biomaterials Applications

SN - 0885-3282

IS - 4

ER -