TUTCRIS - Tampereen teknillinen yliopisto

TUTCRIS

Intrapleural photodynamic therapy for mesothelioma: What place and which future?

Tutkimustuotosvertaisarvioitu

Yksityiskohdat

AlkuperäiskieliEnglanti
Sivut2237-2245
Sivumäärä9
JulkaisuAnnals of Thoracic Surgery
Vuosikerta99
Numero6
DOI - pysyväislinkit
TilaJulkaistu - 1 kesäkuuta 2015
OKM-julkaisutyyppiA2 Katsausartikkeli

Tiivistelmä

In the surgical multimodal management of malignant pleural mesothelioma, it seems crucial to proceed with an efficient local adjuvant treatment to kill residual tumor cells. Intrapleural photodynamic therapy has recently emerged as a potential candidate in this goal. In this review, we analyzed and classified 16 articles in which patients with malignant pleural mesothelioma received intrapleural photodynamic therapy after maximal surgical resection. The toxicity, effect on survival, and development of the technique were assessed. After two decades of clinical studies, intrapleural photodynamic therapy after surgical resection became a safe treatment that significantly improved the survival of patients.