TUTCRIS - Tampereen teknillinen yliopisto

TUTCRIS

Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms

Tutkimustuotosvertaisarvioitu

Standard

Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms. / Pyysalo, Liisa; Luostarinen, Tapio; Keski-Nisula, Leo; Öhman, Juha.

julkaisussa: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vuosikerta 84, Nro 8, 2013, s. 888-892.

Tutkimustuotosvertaisarvioitu

Harvard

Pyysalo, L, Luostarinen, T, Keski-Nisula, L & Öhman, J 2013, 'Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms', JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, Vuosikerta. 84, Nro 8, Sivut 888-892. https://doi.org/10.1136/jnnp-2012-303073

APA

Pyysalo, L., Luostarinen, T., Keski-Nisula, L., & Öhman, J. (2013). Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 84(8), 888-892. https://doi.org/10.1136/jnnp-2012-303073

Vancouver

Pyysalo L, Luostarinen T, Keski-Nisula L, Öhman J. Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2013;84(8):888-892. https://doi.org/10.1136/jnnp-2012-303073

Author

Pyysalo, Liisa ; Luostarinen, Tapio ; Keski-Nisula, Leo ; Öhman, Juha. / Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms. Julkaisussa: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2013 ; Vuosikerta 84, Nro 8. Sivut 888-892.

Bibtex - Lataa

@article{516ab3a825274e25a8b31ca3fb0db49a,
title = "Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms",
abstract = "Background and aim: Subarachnoid haemorrhage (SAH) patients have an excess mortality proportion in long-term outcome studies because of the high rate of cerebrovascular and cardiovascular deaths. The aim of the present study was to assess the excess long-term mortality among patients with unruptured aneurysms with no previous SAH and to compare excess mortality after coiling, clipping and without treatment. Methods: Between 1989 and 1999, a total of 1294 patients with intracranial aneurysms were admitted to our hospital. Of these, 1154 had previous SAH and were excluded leaving 140 patients with 178 intracranial unruptured aneurysms as the study population. The patients were followed up until death or by the end of April 2011. Causes of death were determined. Relative survival ratios (RSRs) were calculated and compared with the matched general population. Results: Mean follow-up time was 13 years (range 1-19). During the follow-up period, 36{\%} of patients died. Death was caused by cerebrovascular event in half of the cases. There were 12{\%} excess mortality at 15 years in men and 35{\%} excess mortality in women compared with general population. Excess mortality among women over 50 years was significantly higher than that among men ( p=0.018). Conclusions: Patients with untreated unruptured aneurysms have 50{\%} excess long-term mortality compared with general population. Men with treated unruptured aneurysms have a survival proportion comparable with matched general population. Women, instead, have 28{\%} excess mortality after surgical treatment and 23{\%} excess mortality after endovascular treatment of unruptured aneurysms.",
author = "Liisa Pyysalo and Tapio Luostarinen and Leo Keski-Nisula and Juha {\"O}hman",
year = "2013",
doi = "10.1136/jnnp-2012-303073",
language = "English",
volume = "84",
pages = "888--892",
journal = "JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY",
issn = "0022-3050",
publisher = "BMJ Publishing Group",
number = "8",

}

RIS (suitable for import to EndNote) - Lataa

TY - JOUR

T1 - Long-term excess mortality of patients with treated and untreated unruptured intracranial aneurysms

AU - Pyysalo, Liisa

AU - Luostarinen, Tapio

AU - Keski-Nisula, Leo

AU - Öhman, Juha

PY - 2013

Y1 - 2013

N2 - Background and aim: Subarachnoid haemorrhage (SAH) patients have an excess mortality proportion in long-term outcome studies because of the high rate of cerebrovascular and cardiovascular deaths. The aim of the present study was to assess the excess long-term mortality among patients with unruptured aneurysms with no previous SAH and to compare excess mortality after coiling, clipping and without treatment. Methods: Between 1989 and 1999, a total of 1294 patients with intracranial aneurysms were admitted to our hospital. Of these, 1154 had previous SAH and were excluded leaving 140 patients with 178 intracranial unruptured aneurysms as the study population. The patients were followed up until death or by the end of April 2011. Causes of death were determined. Relative survival ratios (RSRs) were calculated and compared with the matched general population. Results: Mean follow-up time was 13 years (range 1-19). During the follow-up period, 36% of patients died. Death was caused by cerebrovascular event in half of the cases. There were 12% excess mortality at 15 years in men and 35% excess mortality in women compared with general population. Excess mortality among women over 50 years was significantly higher than that among men ( p=0.018). Conclusions: Patients with untreated unruptured aneurysms have 50% excess long-term mortality compared with general population. Men with treated unruptured aneurysms have a survival proportion comparable with matched general population. Women, instead, have 28% excess mortality after surgical treatment and 23% excess mortality after endovascular treatment of unruptured aneurysms.

AB - Background and aim: Subarachnoid haemorrhage (SAH) patients have an excess mortality proportion in long-term outcome studies because of the high rate of cerebrovascular and cardiovascular deaths. The aim of the present study was to assess the excess long-term mortality among patients with unruptured aneurysms with no previous SAH and to compare excess mortality after coiling, clipping and without treatment. Methods: Between 1989 and 1999, a total of 1294 patients with intracranial aneurysms were admitted to our hospital. Of these, 1154 had previous SAH and were excluded leaving 140 patients with 178 intracranial unruptured aneurysms as the study population. The patients were followed up until death or by the end of April 2011. Causes of death were determined. Relative survival ratios (RSRs) were calculated and compared with the matched general population. Results: Mean follow-up time was 13 years (range 1-19). During the follow-up period, 36% of patients died. Death was caused by cerebrovascular event in half of the cases. There were 12% excess mortality at 15 years in men and 35% excess mortality in women compared with general population. Excess mortality among women over 50 years was significantly higher than that among men ( p=0.018). Conclusions: Patients with untreated unruptured aneurysms have 50% excess long-term mortality compared with general population. Men with treated unruptured aneurysms have a survival proportion comparable with matched general population. Women, instead, have 28% excess mortality after surgical treatment and 23% excess mortality after endovascular treatment of unruptured aneurysms.

UR - http://www.scopus.com/inward/record.url?scp=84879947090&partnerID=8YFLogxK

U2 - 10.1136/jnnp-2012-303073

DO - 10.1136/jnnp-2012-303073

M3 - Article

VL - 84

SP - 888

EP - 892

JO - JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

JF - JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

SN - 0022-3050

IS - 8

ER -