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Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting

Tutkimustuotosvertaisarvioitu

Standard

Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting. / Barberi, Jacopo; Nommeots-Nomm, Amy; Fiume, Elisa; Verné, Enrica; Massera, Jonathan; Baino, Francesco.

julkaisussa: Biomedical Glasses, Vuosikerta 5, Nro 1, 2019, s. 140-147.

Tutkimustuotosvertaisarvioitu

Harvard

Barberi, J, Nommeots-Nomm, A, Fiume, E, Verné, E, Massera, J & Baino, F 2019, 'Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting', Biomedical Glasses, Vuosikerta. 5, Nro 1, Sivut 140-147. https://doi.org/10.1515/bglass-2019-0012

APA

Barberi, J., Nommeots-Nomm, A., Fiume, E., Verné, E., Massera, J., & Baino, F. (2019). Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting. Biomedical Glasses, 5(1), 140-147. https://doi.org/10.1515/bglass-2019-0012

Vancouver

Barberi J, Nommeots-Nomm A, Fiume E, Verné E, Massera J, Baino F. Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting. Biomedical Glasses. 2019;5(1):140-147. https://doi.org/10.1515/bglass-2019-0012

Author

Barberi, Jacopo ; Nommeots-Nomm, Amy ; Fiume, Elisa ; Verné, Enrica ; Massera, Jonathan ; Baino, Francesco. / Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting. Julkaisussa: Biomedical Glasses. 2019 ; Vuosikerta 5, Nro 1. Sivut 140-147.

Bibtex - Lataa

@article{8702626e862a4e33b5ac2d1f4921df7a,
title = "Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting",
abstract = "Since the discovery of 45S5 Bioglass{\circledR} by Larry Hench, bioactive glasses have been widely studied as bone substitute materials and, in more recent years, have also shown great promise for producing three-dimensional scaffolds. The development of additive manufacturing techniques and their application in bone tissue engineering allows the design and fabrication of complex structures with controlled porosity. However, achieving strong and mechanically-reliable bioactive glass scaffolds is still a great challenge. Furthermore, there is a relative paucity of studies reporting an exhaustive assessment of other mechanical properties than compressive strength of glass-derived scaffolds. This research work aimed at determining key mechanical properties of silicate SiO2-Na2O-K2OMgO-CaO-P2O5 glass scaffolds fabricated by robocasting and exhibiting a porosity gradient. When tested in compression, these scaffolds had a strength of 6 MPa, a Young's modulus around 340 MPa, a fracture energy of 93 kJ/m3 and a Weibull modulus of 3, which provides a quantification of the scaffold reliability and reproducibility. Robocasting was a suitable manufacturing method to obtain structures with favorable porosity and mechanical properties comparable to those of the human cancellous bone, which is fundamental regarding osteointegration of bone implants.",
keywords = "Bioactive glass, Mechanical properties, Robocasting, Scaffold",
author = "Jacopo Barberi and Amy Nommeots-Nomm and Elisa Fiume and Enrica Vern{\'e} and Jonathan Massera and Francesco Baino",
note = "EXT={"}Nommeots-Nomm, Amy{"}",
year = "2019",
doi = "10.1515/bglass-2019-0012",
language = "English",
volume = "5",
pages = "140--147",
journal = "Biomedical Glasses",
issn = "2299-3932",
publisher = "de Gruyter",
number = "1",

}

RIS (suitable for import to EndNote) - Lataa

TY - JOUR

T1 - Mechanical characterization of pore-graded bioactive glass scaffolds produced by robocasting

AU - Barberi, Jacopo

AU - Nommeots-Nomm, Amy

AU - Fiume, Elisa

AU - Verné, Enrica

AU - Massera, Jonathan

AU - Baino, Francesco

N1 - EXT="Nommeots-Nomm, Amy"

PY - 2019

Y1 - 2019

N2 - Since the discovery of 45S5 Bioglass® by Larry Hench, bioactive glasses have been widely studied as bone substitute materials and, in more recent years, have also shown great promise for producing three-dimensional scaffolds. The development of additive manufacturing techniques and their application in bone tissue engineering allows the design and fabrication of complex structures with controlled porosity. However, achieving strong and mechanically-reliable bioactive glass scaffolds is still a great challenge. Furthermore, there is a relative paucity of studies reporting an exhaustive assessment of other mechanical properties than compressive strength of glass-derived scaffolds. This research work aimed at determining key mechanical properties of silicate SiO2-Na2O-K2OMgO-CaO-P2O5 glass scaffolds fabricated by robocasting and exhibiting a porosity gradient. When tested in compression, these scaffolds had a strength of 6 MPa, a Young's modulus around 340 MPa, a fracture energy of 93 kJ/m3 and a Weibull modulus of 3, which provides a quantification of the scaffold reliability and reproducibility. Robocasting was a suitable manufacturing method to obtain structures with favorable porosity and mechanical properties comparable to those of the human cancellous bone, which is fundamental regarding osteointegration of bone implants.

AB - Since the discovery of 45S5 Bioglass® by Larry Hench, bioactive glasses have been widely studied as bone substitute materials and, in more recent years, have also shown great promise for producing three-dimensional scaffolds. The development of additive manufacturing techniques and their application in bone tissue engineering allows the design and fabrication of complex structures with controlled porosity. However, achieving strong and mechanically-reliable bioactive glass scaffolds is still a great challenge. Furthermore, there is a relative paucity of studies reporting an exhaustive assessment of other mechanical properties than compressive strength of glass-derived scaffolds. This research work aimed at determining key mechanical properties of silicate SiO2-Na2O-K2OMgO-CaO-P2O5 glass scaffolds fabricated by robocasting and exhibiting a porosity gradient. When tested in compression, these scaffolds had a strength of 6 MPa, a Young's modulus around 340 MPa, a fracture energy of 93 kJ/m3 and a Weibull modulus of 3, which provides a quantification of the scaffold reliability and reproducibility. Robocasting was a suitable manufacturing method to obtain structures with favorable porosity and mechanical properties comparable to those of the human cancellous bone, which is fundamental regarding osteointegration of bone implants.

KW - Bioactive glass

KW - Mechanical properties

KW - Robocasting

KW - Scaffold

U2 - 10.1515/bglass-2019-0012

DO - 10.1515/bglass-2019-0012

M3 - Article

VL - 5

SP - 140

EP - 147

JO - Biomedical Glasses

JF - Biomedical Glasses

SN - 2299-3932

IS - 1

ER -