TUTCRIS - Tampereen teknillinen yliopisto

TUTCRIS

Nanodevice Arrays for Peripheral Nerve Fascicle Activation Using Ultrasound Energy-harvesting

Tutkimustuotosvertaisarvioitu

Yksityiskohdat

AlkuperäiskieliEnglanti
Sivut919-930
JulkaisuIEEE Transactions on Nanotechnology
Vuosikerta16
Numero6
DOI - pysyväislinkit
TilaJulkaistu - 2017
OKM-julkaisutyyppiA1 Alkuperäisartikkeli

Tiivistelmä

We propose the use of wireless, energy-harvesting, implanted nanodevice arrays with electrodes for selective stimulation of peripheral nerves in the human body. We calculate the input ultrasound energy and harvested power for single fixed-size nanowire-based nanodevices at different tissue depths and compare these with the current and voltage levels required for peripheral neural stimulation. We model the dimensioning of arrays of nanodevices, embedded in biocompatible tissue patches, to meet these neural stimulation requirements. Selectivity of activation of particular nerve bundles requires that the output voltage and current of the array can be varied to increase or decrease penetration into the neural tissue. This variation can be achieved by changing the energised area of the array and/or by decreasing the incident ultrasound power. However, the array must be implanted horizontally relative to the incident ultrasound as any tilting of the nanodevices will reduce the harvested energy. The proposed approach provides a long-term implant solution for nerve stimulation that allows the patient greater freedom of movement than with embedded tethered electrodes.

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