TUTCRIS - Tampereen teknillinen yliopisto

TUTCRIS

Netmes: Assessing gene network inference algorithms by network-based measures

Tutkimustuotosvertaisarvioitu

Yksityiskohdat

AlkuperäiskieliEnglanti
JulkaisuEvolutionary Bioinformatics
Vuosikerta10
DOI - pysyväislinkit
TilaJulkaistu - 7 joulukuuta 2013
OKM-julkaisutyyppiA1 Alkuperäisartikkeli

Tiivistelmä

Gene regulatory network inference (GRNI) algorithms are essential for efficiently utilizing large-scale microarray datasets to elucidate biochemical interactions among molecules in a cell. Recently, the combination of network-based error measures complemented with an ensemble approach became popular for assessing the inference performance of the GRNI algorithms. For this reason, we developed a software package to facilitate the usage of such metrics. In this paper, we present netmes, an R software package that allows the assessment of GRNI algorithms. The software package netmes is available from the R-Forge web site https://r-forge.r-project.org/projects/netmes/.