TUTCRIS - Tampereen teknillinen yliopisto


Nocturnal Heart Rate Variability Spectrum Characterization in Preschool Children with Asthmatic Symptoms



JulkaisuIEEE Journal of Biomedical and Health Informatics
Varhainen verkossa julkaisun päivämäärä16 marraskuuta 2017
DOI - pysyväislinkit
TilaJulkaistu - syyskuuta 2018
OKM-julkaisutyyppiA1 Alkuperäisartikkeli


Asthma is a chronic lung disease that usually develops during chilhood. Despite that symptoms can almost be controlled with medication, early diagnosis is desirable in order to reduce permanent airway obstruction risk. It has been suggested that abnormal parasympathetic nervous system (PSNS) activity might be closely related with the pathogenesis of asthma, and that this PSNS activity could be reflected in cardiac vagal control. In this work, an index to measure the spectral regularity of the high frequency (HF) component of heart rate variability (HRV) spectrum, named peakness (P), is proposed. Three different implementations of P, based on electrocardiogram (ECG) recordings, impedance pneumography (IP) recordings and a combination of both, were employed in the characterization of a group of pre-school children classified attending to their risk of developing asthma. Peakier componentswere observed in the HF band of those children classified as high-risk (p < 0.005), who also presented reduced sympathvoagal balance. Results suggest that high-risk of developing asthma might be related with a lack of adaptability of PSNS.