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Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators

Tutkimustuotosvertaisarvioitu

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Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators. / Webb, R. Chad; Pielak, Rafal M.; Bastien, Philippe; Ayers, Joshua; Niittynen, Juha; Kurniawan, Jonas; Manco, Megan; Lin, Athena; Cho, Nam Heon; Malyrchuk, Viktor; Balooch, Guive; Rogers, John A.

julkaisussa: PLoS ONE, Vuosikerta 10, Nro 2, e0118131, 06.02.2015.

Tutkimustuotosvertaisarvioitu

Harvard

Webb, RC, Pielak, RM, Bastien, P, Ayers, J, Niittynen, J, Kurniawan, J, Manco, M, Lin, A, Cho, NH, Malyrchuk, V, Balooch, G & Rogers, JA 2015, 'Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators', PLoS ONE, Vuosikerta. 10, Nro 2, e0118131. https://doi.org/10.1371/journal.pone.0118131

APA

Webb, R. C., Pielak, R. M., Bastien, P., Ayers, J., Niittynen, J., Kurniawan, J., ... Rogers, J. A. (2015). Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators. PLoS ONE, 10(2), [e0118131]. https://doi.org/10.1371/journal.pone.0118131

Vancouver

Author

Webb, R. Chad ; Pielak, Rafal M. ; Bastien, Philippe ; Ayers, Joshua ; Niittynen, Juha ; Kurniawan, Jonas ; Manco, Megan ; Lin, Athena ; Cho, Nam Heon ; Malyrchuk, Viktor ; Balooch, Guive ; Rogers, John A. / Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators. Julkaisussa: PLoS ONE. 2015 ; Vuosikerta 10, Nro 2.

Bibtex - Lataa

@article{dde3f8b2f48c43c08b14b4d2d158cae4,
title = "Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators",
abstract = "Measurements of the thermal transport properties of the skin can reveal changes in physical and chemical states of relevance to dermatological health, skin structure and activity, thermoregulation and other aspects of human physiology. Existing methods for in vivo evaluations demand complex systems for laser heating and infrared thermography, or they require rigid, invasive probes; neither can apply to arbitrary regions of the body, offers modes for rapid spatial mapping, or enables continuous monitoring outside of laboratory settings. Here we describe human clinical studies using mechanically soft arrays of thermal actuators and sensors that laminate onto the skin to provide rapid, quantitative in vivo determination of both the thermal conductivity and thermal diffusivity, in a completely non-invasive manner. Comprehensive analysis of measurements on six different body locations of each of twenty-five human subjects reveal systematic variations and directional anisotropies in the characteristics, with correlations to the thicknesses of the epidermis (EP) and stratum corneum (SC) determined by optical coherence tomography, and to the water content assessed by electrical impedance based measurements. Multivariate statistical analysis establishes four distinct locations across the body that exhibit different physical properties: heel, cheek, palm, and wrist/volar forearm/dorsal forearm. The data also demonstrate that thermal transport correlates negatively with SC and EP thickness and positively with water content, with a strength of correlation that varies from region to region, e.g., stronger in the palmar than in the follicular regions.",
author = "Webb, {R. Chad} and Pielak, {Rafal M.} and Philippe Bastien and Joshua Ayers and Juha Niittynen and Jonas Kurniawan and Megan Manco and Athena Lin and Cho, {Nam Heon} and Viktor Malyrchuk and Guive Balooch and Rogers, {John A.}",
year = "2015",
month = "2",
day = "6",
doi = "10.1371/journal.pone.0118131",
language = "English",
volume = "10",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "2",

}

RIS (suitable for import to EndNote) - Lataa

TY - JOUR

T1 - Thermal transport characteristics of human skin measured in vivo using ultrathin conformal arrays of thermal sensors and actuators

AU - Webb, R. Chad

AU - Pielak, Rafal M.

AU - Bastien, Philippe

AU - Ayers, Joshua

AU - Niittynen, Juha

AU - Kurniawan, Jonas

AU - Manco, Megan

AU - Lin, Athena

AU - Cho, Nam Heon

AU - Malyrchuk, Viktor

AU - Balooch, Guive

AU - Rogers, John A.

PY - 2015/2/6

Y1 - 2015/2/6

N2 - Measurements of the thermal transport properties of the skin can reveal changes in physical and chemical states of relevance to dermatological health, skin structure and activity, thermoregulation and other aspects of human physiology. Existing methods for in vivo evaluations demand complex systems for laser heating and infrared thermography, or they require rigid, invasive probes; neither can apply to arbitrary regions of the body, offers modes for rapid spatial mapping, or enables continuous monitoring outside of laboratory settings. Here we describe human clinical studies using mechanically soft arrays of thermal actuators and sensors that laminate onto the skin to provide rapid, quantitative in vivo determination of both the thermal conductivity and thermal diffusivity, in a completely non-invasive manner. Comprehensive analysis of measurements on six different body locations of each of twenty-five human subjects reveal systematic variations and directional anisotropies in the characteristics, with correlations to the thicknesses of the epidermis (EP) and stratum corneum (SC) determined by optical coherence tomography, and to the water content assessed by electrical impedance based measurements. Multivariate statistical analysis establishes four distinct locations across the body that exhibit different physical properties: heel, cheek, palm, and wrist/volar forearm/dorsal forearm. The data also demonstrate that thermal transport correlates negatively with SC and EP thickness and positively with water content, with a strength of correlation that varies from region to region, e.g., stronger in the palmar than in the follicular regions.

AB - Measurements of the thermal transport properties of the skin can reveal changes in physical and chemical states of relevance to dermatological health, skin structure and activity, thermoregulation and other aspects of human physiology. Existing methods for in vivo evaluations demand complex systems for laser heating and infrared thermography, or they require rigid, invasive probes; neither can apply to arbitrary regions of the body, offers modes for rapid spatial mapping, or enables continuous monitoring outside of laboratory settings. Here we describe human clinical studies using mechanically soft arrays of thermal actuators and sensors that laminate onto the skin to provide rapid, quantitative in vivo determination of both the thermal conductivity and thermal diffusivity, in a completely non-invasive manner. Comprehensive analysis of measurements on six different body locations of each of twenty-five human subjects reveal systematic variations and directional anisotropies in the characteristics, with correlations to the thicknesses of the epidermis (EP) and stratum corneum (SC) determined by optical coherence tomography, and to the water content assessed by electrical impedance based measurements. Multivariate statistical analysis establishes four distinct locations across the body that exhibit different physical properties: heel, cheek, palm, and wrist/volar forearm/dorsal forearm. The data also demonstrate that thermal transport correlates negatively with SC and EP thickness and positively with water content, with a strength of correlation that varies from region to region, e.g., stronger in the palmar than in the follicular regions.

U2 - 10.1371/journal.pone.0118131

DO - 10.1371/journal.pone.0118131

M3 - Article

VL - 10

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 2

M1 - e0118131

ER -