Water: A Suitable Medium for the Petasis Borono-Mannich Reaction
Tutkimustuotos › › vertaisarvioitu
Yksityiskohdat
| Alkuperäiskieli | Englanti |
|---|---|
| Sivut | 1859-1863 |
| Sivumäärä | 5 |
| Julkaisu | European Journal of Organic Chemistry |
| Numero | 12 |
| DOI - pysyväislinkit | |
| Tila | Julkaistu - huhtikuuta 2009 |
| Julkaistu ulkoisesti | Kyllä |
| OKM-julkaisutyyppi | A1 Alkuperäisartikkeli |
Tiivistelmä
Water was used as the solvent in the Petasis borono-Mannich reaction. With the use of salicylaldehyde, secondary amines and boronic acids, several alkylaminophenols were obtained in considerably high yields in water. By using the same methodology, 2H-chromenes were prepared with the use of vinyl boronic acids. The reaction mechanism was studied by DFT calculations, and the results obtained corroborate the solvent effect experimentally observed. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)